1. Anti-infection
  2. HIV
  3. Fostemsavir

Fostemsavir (Synonyms: BMS-663068)

Cat. No.: HY-15440A Purity: 99.57%
Handling Instructions

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.

For research use only. We do not sell to patients.

Fostemsavir Chemical Structure

Fostemsavir Chemical Structure

CAS No. : 864953-29-7

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 231 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 231 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.

IC50 & Target

HIV-1[1]

In Vivo

Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

583.49

Formula

C₂₅H₂₆N₇O₈P

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (171.38 mM)

H2O : 20 mg/mL (34.28 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7138 mL 8.5691 mL 17.1383 mL
5 mM 0.3428 mL 1.7138 mL 3.4277 mL
10 mM 0.1714 mL 0.8569 mL 1.7138 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Fostemsavir
Cat. No.:
HY-15440A
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