Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000)  (Synonyms: PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture)

Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface^[1].

Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) binds to the hydroxyl groups on the surface of magnetic nanoparticles through its amino groups, forms a stable coating layer, prevents the agglomeration and sedimentation of magnetic nanoparticles. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) modifies magnetic nanoparticles, improves biocompatibility, and can be used as an antibody coupling platform^[2].
Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) acts as a cationic polymer, forms a polyelectrolyte complex (PEC) with anionic methacrylated gellan gum (GG-MA), thereby forming a semipermeable membrane around the GG-MA hydrogel. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) regulate the permeability of GG-MA/PLL PEC beads, allowing the free diffusion of small molecules while preventing the entry of large molecules, thereby achieving the immune isolation of cells^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

150000-300000

(C₆H₁₄N₂O₂)n.nBrH

25988-63-0

Liquid (Density: 1.053 g/cm³)

Colorless to light yellow

CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Br-].[n]

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. D Mazia, et al. Adhesion of cells to surfaces coated with polylysine. Applications to electron microscopy. J Cell Biol. 1975 Jul;66(1):198-200.  [Content Brief]

  [2]. Kubovcikova M, et al. Poly-L-lysine designed magnetic nanoparticles for combined hyperthermia, magnetic resonance imaging and cancer cell detection. Journal of Magnetism and Magnetic Materials, 2019, 475: 316-326.

  [3]. Vieira S, et al., Methacrylated Gellan Gum/Poly-l-lysine Polyelectrolyte Complex Beads for Cell-Based Therapies. ACS Biomater Sci Eng. 2021 Oct 11;7(10):4898-4913.  [Content Brief]