Poly-L-lysine hydrobromide (MW 150000-300000)
Based on 1 Customer Validation
Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface.
For research use only. We do not sell to patients.
- CAS No.: 25988-63-0
- Formula: C8H19BrN2O
- Molecular Weight:150000-300000
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-126437B
Poly-L-lysine hydrobromide (MW 70000-150000) -
HY-126437I
Poly-L-lysine hydrobromide (MW 1000-5000) -
HY-126437D
Poly-L-lysine hydrobromide (MW ＞300000) -
HY-126436A
Poly-L-ornithine hydrobromide (MW 30000-70000) -
HY-126437J
Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) -
HY-126437E
Poly-L-lysine hydrobromide (MW 15000-30000) -
HY-126437H
Poly-L-lysine hydrobromide (MW 4000-15000) -
HY-126437K
Poly-L-lysine solution (0.01%, sterile-filtered, MW 70000-150000) -
HY-126437
Poly-L-lysine hydrobromide (MW 30000-70000) -
HY-139201A
Poly-D-lysine hydrobromide (MW 70000-150000) -
HY-139201
Poly-D-lysine hydrobromide (MW 30000-70000) -
HY-139201B
Poly-D-lysine hydrobromide (MW 84000)
Biological Activity
Description
In Vitro
Poly-L-lysine (hydrobromide) (MW 150000-300000) binds to the hydroxyl groups on the surface of magnetic nanoparticles through its amino groups, forms a stable coating layer, prevents the agglomeration and sedimentation of magnetic nanoparticles. Poly-L-lysine (hydrobromide) (MW 150000-300000) modifies magnetic nanoparticles, improves biocompatibility, and can be used as an antibody coupling platform[2].
Poly-L-lysine (hydrobromide) (MW 150000-300000) acts as a cationic polymer, forms a polyelectrolyte complex (PEC) with anionic methacrylated gellan gum (GG-MA), thereby forming a semipermeable membrane around the GG-MA hydrogel. Poly-L-lysine (hydrobromide) (MW 150000-300000) regulate the permeability of GG-MA/PLL PEC beads, allowing the free diffusion of small molecules while preventing the entry of large molecules, thereby achieving the immune isolation of cells[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25988-63-0
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Appearance Solid
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Molecular Weight 150000-300000
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Formula C8H19BrN2O
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Color White to yellow
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SMILES
CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Br-].[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
H2O : 25 mg/mL (Need ultrasonic)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL; Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL; Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. D Mazia, et al. Adhesion of cells to surfaces coated with polylysine. Applications to electron microscopy. J Cell Biol. 1975 Jul;66(1):198-200. [Content Brief]
[3]. Vieira S, et al., Methacrylated Gellan Gum/Poly-l-lysine Polyelectrolyte Complex Beads for Cell-Based Therapies. ACS Biomater Sci Eng. 2021 Oct 11;7(10):4898-4913. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Poly-L-lysine hydrobromide (MW 150000-300000) Related Classifications
HY-126437C Related Classifications
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