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Poly-D-lysine hydrobromide (MW 30000-70000) 

Cat. No.: HY-139201
Handling Instructions

Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide (MW 30000-70000) removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC.

For research use only. We do not sell to patients.

Poly-D-lysine hydrobromide (MW 30000-70000) Chemical Structure

Poly-D-lysine hydrobromide (MW 30000-70000) Chemical Structure

CAS No. : 27964-99-4

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Description

Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide (MW 30000-70000) removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC[1][2].

In Vitro

Poly-D-lysine is immunogenic in rabbits only when injected at low doses[1].
The approximate concentration of Poly-D-lysine (PDL) needed to lower the amount of PrPres by 50% corresponds to ~0.8 μg/mL or 50 nM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

30000-70000

Formula

(C₆H₁₄N₂O₂)x.xBrH

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Poly-D-lysine hydrobromide (MW 30000-70000)
Cat. No.:
HY-139201
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