Poly-L-lysine hydrobromide (MW 15000-30000)

Cat. No.: HY-126437E: Data Sheet
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Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) is an amino acid polymer with positive charge, and it serves as a non-specific attachment factor for cells. Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) can be used for gene delivery and the construction of nano-delivery systems.

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Poly-L-lysine hydrobromide (MW 15000-30000) Chemical Structure

CAS No. : 25988-63-0

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5 mg	In-stock	Estimated Time of Arrival: December 31
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Other Forms of Poly-L-lysine hydrobromide (MW 15000-30000):

Poly-L-lysine hydrobromide (MW 30000-70000) In-stock

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Description	Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) is an amino acid polymer with positive charge, and it serves as a non-specific attachment factor for cells. Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) can be used for gene delivery and the construction of nano-delivery systems^[1]^[2].
In Vitro	Poly-L-lysine hydrobromide (MW 15000-30000) binds to negatively charged plasmid DNA (pDNA) through electrostatic interaction, forming a complex (polyplex), thereby introducing genes into cells. Due to its large molecular weight and abundant positive charge, it can strongly condense pDNA to form small and stable nanoparticles, making it an effective carrier when CaCl₂ is absent ^[1]. Poly-L-lysine hydrobromide (MW 15000-30000) can be used to construct a nanoscale platform for delivering deoxyribonucleases (DZs). Its core function is to bridge titanium dioxide (TiO₂) nanoparticles and negatively charged Dz² through electrostatic interaction^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Poly-L-lysine hydrobromide (MW 15000-30000) Related Antibodies
Molecular Weight	15000-30000
Formula	C₈H₁₉BrN₂O
CAS No.	25988-63-0
Appearance	Solid
Color	White to off-white
SMILES	CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Br-].[n]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility	In Vitro: H₂O : 50 mg/mL (Need ultrasonic and warming) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: [email protected] Technical Support: [email protected]
Purity & Documentation	Select Batch: Data Sheet (268 KB) SDS (393 KB) COA (246 KB) Handling Instructions (2659 KB)
References	[1]. Xie SX, et al. Calcium enhances gene expression when using low molecular weight poly-l-lysine delivery vehicles. Int J Pharm. 2018 Aug 25;547(1-2):274-281. [Content Brief] [2]. Repkova M, et al. Efficient inhibition of influenza A viral replication in cells by deoxyribozymes delivered by nanocomposites. Int J Antimicrob Agents. 2017 Jun;49(6):703-708. [Content Brief]