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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
cis-trans isomerization
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "cis-trans isomerization" in MCE Product Catalog:
1
1 Cited Publications
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC50 of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development .
Cat. No.: HY-P2930
CAS No.: 95076-93-0
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Research Areas:
Peptidylprolyl isomerase is an enzyme that catalyzes the cis-trans isomerization of peptidylprolyl amino groups. Peptidylprolyl isomerase may be involved in cellulase modification. Peptidylprolyl isomerase also functions as a chaperone protein .
Cat. No.: HY-N15785
CAS No.: 2098674-45-2
Category:
Target:
Cat. No.: HY-E71348
Target:
Research Areas:
ζ-Carotene isomerase (EC 5.2.1.12) catalyses the cis-trans isomerization of the 15-15' carbon-carbon double bond in 9,15,9'-tricis-ζ-Carotene, which is required for biosynthesis of all plant carotenoids. Requires heme b.
Cat. No.: HY-187112
CAS No.: 202739-37-5
Cat. No.: HY-W392267
CAS No.: 1504-55-8
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α-Methylcinnamyl alcohol is a derivative of Cinnamyl Alcohol (HY-Y0078) .
Cat. No.: HY-180985
Azo-PROTAC-4C-cis is a BCR-ABL PROTAC degrader, and its degradation efficiency of BCR-ABL is much lower than that of its trans isomer Azo-PROTAC-4C-trans (HY-180983). Azo-PROTAC-4C-cis is the product of the conformational transformation of Azo-PROTAC-4C-trans under ultraviolet (UV) light irradiation. Azo-PROTAC-4C-cis can be converted into highly active Azo-PROTAC-4C-trans under visible light, thereby initiating protein degradation. Azo-PROTAC-4C-cis can be used for the study of myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
