10 Results for "

contact sensitization

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "contact sensitization" in MCE Product Catalog:

Cat. No.: HY-Y0912
CAS No.: 94790-37-1
Synonyms: N-HBTU
Research Areas:  

Inflammation/Immunology

HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
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Cat. No.: HY-B1419
CAS No.: 90-01-7
Synonyms: 2-Hydroxybenzyl alcohol; Saligenin
Salicyl alcohol (2-Hydroxybenzyl alcohol; Saligenin) is a phenolic alcohol-type topical anesthetic and strong sensitizer with antiseptic, antibacterial and antipyretic activities. Salicyl alcohol serves as a precursor for salicin synthesis. Salicyl alcohol induces contact dermatitis and eczematous skin reactions, and is a well-known allergen identified in phenolic resins. Salicyl alcohol is isolated from the barks of European aspen (Populus tremula), rowan (Sorbus aucuparia) and willow (Salix spp.). Salicyl alcohol is used in studies related to allergic contact dermatitis .
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Cat. No.: HY-P10940
CAS No.: 845727-63-1
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Ac-RFAAKAA-COOH is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH forms stable covalent adducts with isothiocyanates, resulting in peptide depletion over time. Ac-RFAAKAA-COOH acts as a model peptide in direct peptide reactivity assays, where its chemical reactivity is evaluated via fluorescamine-based free amine assays. Ac-RFAAKAA-COOH can be used in studies related to allergic contact dermatitis and skin sensitization .
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Cat. No.: HY-W009688
CAS No.: 105-76-0
Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice .
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Cat. No.: HY-P5352
CAS No.: 299157-43-0
Target:  

CD44

Research Areas:  

Inflammation/Immunology Cancer

Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a Kd value of 1.65 μM. Hyaluronan-IN-1 blocks CD44-dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma .
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Cat. No.: HY-W335896
CAS No.: 15233-47-3
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

4-(2-Octylamino)diphenylamine is an aromatic amine antioxidant, which is toxic to V. fischeri with an IC50 value of 0.68 mg/mL. 4-(2-Octylamino)diphenylamine induces skin sensitization and contact dermatitis in a local lymph node assay in mice. 4-(2-Octylamino)diphenylamine can be used as an additive in rubber .
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Cat. No.: HY-187232
CAS No.: 2536-05-2
Synonyms: 2,2′-MDI
Target:  

Others

Research Areas:  

Inflammation/Immunology

2,2'-Methylenediphenyl diisocyanate (2,2′-MDI) is a sensitizer and an isomer of methylenediphenyl diisocyanate (MDI). 2,2'-Methylenediphenyl diisocyanate induces contact sensitization upon skin contact. 2,2'-Methylenediphenyl diisocyanate is used in studies of allergic contact dermatitis .
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Cat. No.: HY-119958
CAS No.: 74161-27-6
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

Acamelin is a Benzofuranoquinone compound that acts as a contact sensitizer. It can be isolated from the heartwood of Acacia melanoxylon R. Br., an Australian blackwood. Acamelin induces positive skin reactions and contact allergy in guinea pigs. It is applicable to research related to allergic contact dermatitis .
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Cat. No.: HY-W009688R
CAS No.: 105-76-0
Dibutyl maleate (Standard) is the analytical standard of Dibutyl maleate (HY-W009688). This product is intended for research and analytical applications. Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice .
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Cat. No.: HY-184853
CAS No.: 99-84-3
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

β-Terpinene is a naturally occurring monoterpene, prohapten/metabolic substrate, and contact allergen inducer, with moderate potency as a sensitizer .β-Terpinene undergoes metabolic activation to epoxides that conjugate with glutathione .β-Terpinene induces contact allergy via reactive allylic epoxide metabolites .β-Terpinene does not significantly reduce growth of Erwinia amylovora at concentrations up to 1500 mg/l .β-Terpinene can be used for the research of Aspergillus flavus infection.
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