Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
copper-free SPAAC
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "copper-free SPAAC" in MCE Product Catalog:
6
6 Cited Publications
Target:
Research Areas:
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target:
Research Areas:
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target:
Research Areas:
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research .
Cat. No.: HY-W588722
CAS No.: 3024705-52-7
Cat. No.: HY-D1625
CAS No.: 2182601-72-3
Cat. No.: HY-W714234
CAS No.: 1352811-59-6
Target:
Research Areas:
Endo-BCN CE-phosphoramidite is a stable and one of the most reactive cyclooctynes for copper-free click chemistry. Unlike dibenzocyclooctyne (DBCO), BCN is reactive both to azides (strain-promoted azyde-alkyne cycloaddition, SPAAC) and tetrazines (inverse electron demand Diels-Alder reaction, IEDDA).
Cat. No.: HY-181228
Target:
Research Areas:
DBCO-PEG10-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 10 PEGs. DBCO-PEG10-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction. DBCO-PEG10-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
Cat. No.: HY-P11428
CAS No.: 2425606-55-7
Research Areas:
Target:
Research Areas:
VHLL-BCN is a ligand targeting the VHL E3 ligase, which can be used for the synthesis of PROTAC molecules. As a key component of the copper-free SPAAC-based rapid synthesis platform for transcription factor PROTACs, VHLL-BCN is applicable to cancer-related research .
Cat. No.: HY-W1124386
CAS No.: 1820756-74-8
Synonyms: SNAP-DBCO
Cat. No.: HY-D2758
CAS No.: 1911598-65-6
Cat. No.: HY-D3339
Cat. No.: HY-D3569
Cat. No.: HY-D3566
Cat. No.: HY-D3571
Cat. No.: HY-D3575
Cat. No.: HY-D3578
Cat. No.: HY-D3482
Cat. No.: HY-D3570
Target:
Research Areas:
AF405 DBCO is a blue fluorescent dye derivative containing a dibenzocyclooctyne (DBCO) group. AF405 DBCO reacts rapidly with azide-labeled biomolecules at room temperature without the need for a metal catalyst, enabling copper-free click chemistry (SPAAC) for applications in live-cell imaging, flow cytometry, super-resolution microscopy, and other research fields .
Cat. No.: HY-185693
Target:
Research Areas:
DBCO2-PEG24 is a non-targeting bivalent DBCO-functionalized shielding agent with a PEG24 spacer, which can be used as a surface shielding control. DBCO2-PEG24 binds to the surface of lipid oligomer-modified siRNA lipopolymer nanoparticles via copper-free click reaction (SPAAC) .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
