12 Results for "

crossbridge

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "crossbridge" in MCE Product Catalog:

Cat. No.: HY-P1883A
Target:  

Fluorescent Dye

Research Areas:  

Infection

Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
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Cat. No.: HY-W141916
CAS No.: 7093-67-6
Synonyms: Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353
Research Areas:  

Infection

Pentaglycine (Tetraglycylglycine; NSC 96353) is a bridging structure composed of five glycine residues. Pentaglycine serves as a characteristic peptidoglycan cross-bridge component of staphylococci and a specific substrate for lysostaphin. Pentaglycine maintains the integrity of the peptidoglycan cell wall of Staphylococcus aureus via peptide chain cross-linking and regulates bacterial growth. Pentaglycine expression is downregulated in high-glucose environments, inhibiting bacterial proliferation. Pentaglycine can be applied to studies related to Staphylococcus aureus infection .
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Cat. No.: HY-P5481
CAS No.: 1807943-24-3
Target:  

Peptides

Research Areas:  

Others

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)
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Cat. No.: HY-P1883
CAS No.: 2857862-12-3
Target:  

Fluorescent Dye

Research Areas:  

Infection

Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
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Cat. No.: HY-P10654
CAS No.: 2861260-80-0
Target:  

TRP Channel

Research Areas:  

Neurological Disease

RhTx is a transient receptor potential vanillin-1 (TRPV1) activator. RhTx can be used to study pain perception .
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Cat. No.: HY-P3350
CAS No.: 2892148-58-0
Target:  

Bacterial

Research Areas:  

Infection

LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
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Cat. No.: HY-101693A
CAS No.: 98326-33-1
Purity:  99.84%
Synonyms: MCI 154 hydrochloride
Research Areas:  

Cardiovascular Disease

Senazodan (MCI 154) (hydrochloride), as a Ca 2+ sensitiser, shows inhibition effect on PDE III .
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Cat. No.: HY-101693
CAS No.: 98326-32-0
Synonyms: MCI 154
Research Areas:  

Cardiovascular Disease

Senazodan (MCI 154) is a Ca 2+ sensitiser, and also shows inhibition effect on PDE III .
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Cat. No.: HY-P3314
CAS No.: 2251119-65-8
Target:  

Somatostatin Receptor

Research Areas:  

Metabolic Disease

Nendratareotide is a somatostatin analogue .
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Cat. No.: HY-P10819
Research Areas:  

Cancer

S9-CMC1 TFA is a covalent peptide lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 value of 2.53 μM. S9-CMC1 TFA specifically recognizes Cys360 in the enzyme-active region. S9-CMC1 TFA inhibits LSD1 activity, increasing H3K4me1 and H3K4me2 levels, leading to G1 cell cycle arrest and apoptosis and inhibiting cell proliferation. S9-CMC1 TFA significantly inhibits tumor growth in A549 xenograft animal models .
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Cat. No.: HY-101693AR
CAS No.: 98326-33-1
Synonyms: MCI 154 hydrochloride (Standard)
Senazodan (hydrochloride) (Standard) is the analytical standard of Senazodan (hydrochloride) (HY-101693A). This product is intended for research and analytical applications. Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III .
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Cat. No.: HY-P11408
CAS No.: 349657-39-2
Target:  

Bombesin Receptor

Research Areas:  

Neurological Disease Cancer

[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14), a synthetic peptide, is a non-selective bombesin receptor agonist. [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) has preferred pEC50 values of 8.06 for the neurotrophin B bombesin receptor (BB1), 8.69 for the gastrin-releasing peptide bombesin receptor (BB2), and 6.71 for the orphan receptor (BB3). [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) can be used to study diseases related to bombesin receptors, such as cancer and neurological disorders .
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