2857862-12-3
Chemical Structure
Bacterial Sortase Substrate III, Abz/DNP
- CAS No.: 2857862-12-3
- Formula:C41H57N11O14
- Molecular Weight:927.96
IUPAC Name: (S)-5-(((2S,3R)-1-((2-(((S)-1-amino-6-((2,4-dinitrophenyl)amino)-1-oxohexan-2-yl)amino)-2-oxoethyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-4-((S)-1-((2-aminobenzoyl)-L-leucyl)pyrrolidine-2-carboxamido)-5-oxopentanoic acid
InChIKey: WRZFAMJIPLOPLJ-OAFPALBKSA-N
SMILES: O=C([C@@H](NC(C1=C(C=CC=C1)N)=O)CC(C)C)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N)=O)CCCCNC3=C(C=C(C=C3)[N+]([O-])=O)[N+]([O-])=O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC2
Biological Activity: Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm[1].
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Bacterial Sortase Substrate III, Abz/DNP | Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm. | |||||||||||||||||||||
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