2. GPCR/G Protein
  3. Bombesin Receptor
  4. [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14)

[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14), a synthetic peptide, is a non-selective bombesin receptor agonist. [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) has preferred pEC50 values of 8.06 for the neurotrophin B bombesin receptor (BB1), 8.69 for the gastrin-releasing peptide bombesin receptor (BB2), and 6.71 for the orphan receptor (BB3). [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) can be used to study diseases related to bombesin receptors, such as cancer and neurological disorders.

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[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14)

[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) Chemical Structure

CAS No. : 349657-39-2

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[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) Related Antibodies

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Description

[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14), a synthetic peptide, is a non-selective bombesin receptor agonist. [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) has preferred pEC50 values of 8.06 for the neurotrophin B bombesin receptor (BB1), 8.69 for the gastrin-releasing peptide bombesin receptor (BB2), and 6.71 for the orphan receptor (BB3). [D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) can be used to study diseases related to bombesin receptors, such as cancer and neurological disorders[1].

Molecular Weight

1013.20

Formula

C44H64N14O10S2
CAS No.
Sequence

{d-Cys}-Asn-Trp-Ala-Val-{d-Ala}-His-Leu-Cys-NH2 (Disulfide bridge Cys1-Cys9)
Sequence Shortening

{d-Cys}-NWAV-{d-Ala}-HLC-NH2 (Disulfide bridge Cys1-Cys9)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[D-Cys6,Asn7,D-Ala11,Cys14]-Bombesin (6-14)349657-39-2Bombesin Receptorgastrin-releasing peptide/bombesin receptor peptide agoniststructure-activity relationshipInhibitorinhibitorinhibit

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