98326-32-0
Chemical Structure
Senazodan
Synonym(s): MCI 154
- CAS No.: 98326-32-0
- Formula:C15H14N4O
- Molecular Weight:266.30
IUPAC Name: 6-(4-(pyridin-4-ylamino)phenyl)-4,5-dihydropyridazin-3(2H)-one
InChIKey: XEBRQQXYWHMEQW-UHFFFAOYSA-N
SMILES: O=C1CCC(C2=CC=C(NC3=CC=NC=C3)C=C2)=NN1
Biological Activity: Senazodan (MCI 154) is a Ca2+ sensitiser, and also shows inhibition effect on PDE III[1][2].
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Senazodan | Senazodan (MCI 154) is a Ca2+ sensitiser, and also shows inhibition effect on PDE III. | |||||||||||||||||||||
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- [1]. Lehtonen LA, et al. Pharmacokinetics and pharmacodynamics of intravenous inotropic agents. Clin Pharmacokinet. 2004;43(3):187-203. [Content Brief]
- [2]. Erhardt L. An emerging role for calcium sensitisation in the treatment of heart failure. Expert Opin Investig Drugs. 2005 Jun;14(6):659-70. [Content Brief]
Keywords