35 Results for "

cucurbitane

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "cucurbitane" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-122949
CAS No.: 91590-76-0
Purity:  ≥97.0%
Momordicine I is a cucurbitane-type triterpenoids. Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation. Momordicine I inhibits glycolysis, lipid metabolism, induces autophagy in HNC cells to suppress head and neck cancer growth. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ. Momordicine I exerts its cardiovascular benefits by upregulating nitric oxide, inhibiting the activity of angiotensin-converting enzyme (ACE), activating the PI3K/Akt pathway, reducing oxidative stress and inflammation. Momordicine I inhibits AKT1, IL-6, and SRC, suggesting its potential application in type 2 diabetes .
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Cat. No.: HY-122954
CAS No.: 81348-84-7
Purity:  ≥98.0%
Momordicoside K is a cucurbitane triterpenoid .
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Cat. No.: HY-N7439
CAS No.: 2149606-17-5
Mogroside VI B, a cucurbitane glucoside, separated from the crude extract of Siraitia grosvenorii. Mogroside VI B shows effect on activating PGC-1α transcription .
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Cat. No.: HY-N7041
11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. 11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
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Cat. No.: HY-N6921
CAS No.: 952481-53-7
11-Oxomogroside III is a cucurbitane triterpene glycoside isolated from in Siraitia grosvenorii fruits .
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Cat. No.: HY-122919
CAS No.: 81348-83-6
Momordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity .
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Cat. No.: HY-N12013
CAS No.: 952481-54-8
11-Oxomogroside IV A (compound 12) is a cucurbitane triterpene glycoside isolated from unripe fruits of Luo Han Guo. 11-Oxomogroside IV A has anti-tumor effects and is cytotoxic to tumor cells SMMC-772 (IC50: 288 μg/mL) .
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Cat. No.: HY-N6928
CAS No.: 88901-37-5
Mogroside III-E is a cucurbitane-type triterpenoid glycoside extracted from Siraitia grosvenorii, and it is an orally active TLR4 inhibitor. Mogroside III-E downregulates the expression of TLR4 and MyD88, and blocks the phosphorylation of downstream ERK, JNK and p38 MAPK molecules; meanwhile, it inhibits TGF-β- or LPS-mediated transdifferentiation of primary pulmonary fibroblasts into myofibroblasts, reduces the content of fibrosis markers such as hydroxyproline, suppresses the pro-fibrotic TGF-β/Smad signaling pathway, and downregulates the levels of inflammatory factors MPO and IL-1β. Mogroside III-E alleviates Bleomycin (HY-108345)-induced pulmonary collagen deposition and inflammatory infiltration in mice. Mogroside III-E can be used in studies related to idiopathic pulmonary fibrosis .
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Cat. No.: HY-N8410
CAS No.: 1011726-62-7
Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .
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Cat. No.: HY-N10672
CAS No.: 191097-54-8
Kuguacin R is a cucurbitane-type triterpenoid that can be extracted from Momordica charantia L. Kuguacin R possess anti-inflammatory, antimicrobial and anti-viral activities .
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Cat. No.: HY-N6578
CAS No.: 89647-62-1
3-epi-Isocucurbitacin B (Compound 5) is a cucurbitane triterpene derived from Trichosanthes kirilowii. 3-epi-Isocucurbitacin B shows significant cytotoxicity to human tumor cells A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT15 .
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Cat. No.: HY-N7040
CAS No.: 2170761-38-1
11-Deoxymogroside IIE is a cucurbitane glycoside, isolated from Siraitia grosvenorii fruits. 11-Deoxymogroside IIE has inhibitory effect against Epstein Barr virus (EBV-EA) activation induced by TPA, shows weak inhibitory effect on (+/-)-(E)-methyl1-2-[E-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR1), a NO donor .
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Cat. No.: HY-N3248
CAS No.: 81371-54-2
Synonyms: Momordicacoside G
Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury .
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Cat. No.: HY-N8041
CAS No.: 88901-43-3
Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1 .
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Cat. No.: HY-N7620
CAS No.: 5942-25-6
Bryonamide B is a cucurbitane-type triterpenoid isolated from Bryonia aspera .
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Cat. No.: HY-N6917
CAS No.: 183374-15-4
Siraitic Acid A is a cucurbitane triterpenoid that can be isolated from the root of S. grosvenori .
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Cat. No.: HY-N6916
CAS No.: 183374-16-5
Siraitic Acid B is a cucurbitane triterpenoid that can be isolated from the root of S. grosvenori .
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Cat. No.: HY-N13100
CAS No.: 1398-78-3
Colocynthin is a cucurbitane triterpenoid glycoside that can be isolated from the bitter apple (Citrullus colocynthis) .
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Cat. No.: HY-N6920
CAS No.: 2096516-68-4
11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori) .
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