81371-54-2
Chemical Structure
Momordicoside G
Synonym(s): Momordicacoside G
- CAS No.: 81371-54-2
- Formula:C37H60O8
- Molecular Weight:632.87
IUPAC Name: (2R,3S,4R,5R,6R)-2-(hydroxymethyl)-6-(((3S,5R,8S,9S,10S,13R,14S,17R)-17-((R,E)-6-methoxy-6-methylhept-4-en-2-yl)-4,4,13,14-tetramethyl-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-2H-5,9-(epoxymethano)cyclopenta[a]phenanthren-3-yl)oxy)tetrahydro-2H-pyran-3
InChIKey: MQGABSJZVJOSCX-JFMWXBCMSA-N
SMILES: C[C@]12[C@@]3([H])[C@@]4(CC[C@@]1([C@]([C@H](C)C/C=C/C(C)(C)OC)([H])CC2)C)[C@@]5([H])[C@@](OC4)(C(C)([C@@H](O[C@]6([H])O[C@@H]([C@@H](O)[C@@H](O)[C@H]6O)CO)CC5)C)C=C3
Biological Activity: Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury[1].
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Momordicoside G | Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury. | |||||||||||||||||||||
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