11-Oxomogroside IV A
Based on 1 Customer Validation
11-Oxomogroside IV A (compound 12) is a cucurbitane triterpene glycoside isolated from unripe fruits of Luo Han Guo. 11-Oxomogroside IV A has anti-tumor effects and is cytotoxic to tumor cells SMMC-772 (IC50: 288 μg/mL).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.22%
- CAS. Nr.: 952481-54-8
- Formel: C54H90O24
- Molecular Weight:1123.28
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 952481-54-8
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Appearance Solid
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Molecular Weight 1123.28
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Formel C54H90O24
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Color White to off-white
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SMILES
C[C@]12[C@](CC=C3[C@@]2([H])CC[C@@H](C3(C)C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)([H])[C@]6([C@](CC1=O)([C@@](CC6)([H])[C@H](C)CC[C@H](C(C)(O)C)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C)C
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Structure Classification
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (44.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Protokoll
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8902 mL | 4.4512 mL | 8.9025 mL | 22.2562 mL |
| 5 mM | 0.1780 mL | 0.8902 mL | 1.7805 mL | 4.4512 mL | |
| 10 mM | 0.0890 mL | 0.4451 mL | 0.8902 mL | 2.2256 mL | |
| 15 mM | 0.0593 mL | 0.2967 mL | 0.5935 mL | 1.4837 mL | |
| 20 mM | 0.0445 mL | 0.2226 mL | 0.4451 mL | 1.1128 mL | |
| 25 mM | 0.0356 mL | 0.1780 mL | 0.3561 mL | 0.8902 mL | |
| 30 mM | 0.0297 mL | 0.1484 mL | 0.2967 mL | 0.7419 mL | |
| 40 mM | 0.0223 mL | 0.1113 mL | 0.2226 mL | 0.5564 mL |