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  5. Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang
  6. 11-Oxomogroside IV A

11-Oxomogroside IV A (compound 12) is a cucurbitane triterpene glycoside isolated from unripe fruits of Luo Han Guo. 11-Oxomogroside IV A has anti-tumor effects and is cytotoxic to tumor cells SMMC-772 (IC50: 288 μg/mL).

For research use only. We do not sell to patients.

11-Oxomogroside IV A

11-Oxomogroside IV A Chemical Structure

CAS No. : 952481-54-8

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Based on 1 publication(s) in Google Scholar

11-Oxomogroside IV A Related Antibodies

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Description

11-Oxomogroside IV A (compound 12) is a cucurbitane triterpene glycoside isolated from unripe fruits of Luo Han Guo. 11-Oxomogroside IV A has anti-tumor effects and is cytotoxic to tumor cells SMMC-772 (IC50: 288 μg/mL)[1].

Molecular Weight

1123.28

Formula

C54H90O24
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@](CC=C3[C@@]2([H])CC[C@@H](C3(C)C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)([H])[C@]6([C@](CC1=O)([C@@](CC6)([H])[C@H](C)CC[C@H](C(C)(O)C)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (44.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8902 mL 4.4512 mL 8.9025 mL
5 mM 0.1780 mL 0.8902 mL 1.7805 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8902 mL 4.4512 mL 8.9025 mL 22.2562 mL
5 mM 0.1780 mL 0.8902 mL 1.7805 mL 4.4512 mL
10 mM 0.0890 mL 0.4451 mL 0.8902 mL 2.2256 mL
15 mM 0.0593 mL 0.2967 mL 0.5935 mL 1.4837 mL
20 mM 0.0445 mL 0.2226 mL 0.4451 mL 1.1128 mL
25 mM 0.0356 mL 0.1780 mL 0.3561 mL 0.8902 mL
30 mM 0.0297 mL 0.1484 mL 0.2967 mL 0.7419 mL
40 mM 0.0223 mL 0.1113 mL 0.2226 mL 0.5564 mL
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11-Oxomogroside IV A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11-Oxomogroside IV A952481-54-8OthersSiraitia grosvenoriLo Han Kuocucurbitane-glycosideunripe fruitcytotoxic activityInhibitorinhibitorinhibit

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