Search Result
Results for "
diamine
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
21
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-173634
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan (LP1) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB (HY-173635) to make antibody agent conjugate (ADC), AZD0516 (HY-173639) .
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- HY-W016750
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Biochemical Assay Reagents
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Others
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Pentane-1,5-diamine dihydrochloride is a putrescine. Pentane-1,5-diamine dihydrochloride can be incorporated into lobeline, but it is not a conventional intermediate in the lysine-to-lobeline synthesis process .
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- HY-108497
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Somatostatin Receptor
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Neurological Disease
Cancer
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L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. L-803087 is >280-fold higher than other somatostatin receptors. L-803087 facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice .
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- HY-P2758
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DAO
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Biochemical Assay Reagents
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Metabolic Disease
Inflammation/Immunology
Cancer
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Diamine oxidase (DAO) is an orally active enzyme. Diamine oxidase catalyzes oxidative deamination of various polyamines. Diamine oxidase degrades histamine and polyamines to maintain the metabolic balance of amines in the body. Diamine oxidase is a key regulatory enzyme in rapidly proliferating tissues such as bone marrow and intestinal mucosa. Diamine oxidase can be used in research related to intestinal diseases, small bowel transplant rejection, histamine intolerance, and other conditions .
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- HY-W017529
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- HY-W115752
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diamine sulfate (99%)
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PEPCK
Aldehyde Dehydrogenase (ALDH)
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Neurological Disease
Metabolic Disease
Cancer
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Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-Km ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP + toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease .
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- HY-W013631
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Biochemical Assay Reagents
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Others
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7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007978
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R-(-)-2,2-Diamino-1,1-binaphthyl
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Biochemical Assay Reagents
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Others
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(R)-[1,1'-Binaphthalene]-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W190915
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Biochemical Assay Reagents
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Others
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4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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- HY-W012684S1
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Ethylenediamine-d4 dihydrochloride
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Isotope-Labeled Compounds
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Others
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Ethane-1,2-diamine-d4 (Ethylenediamine-d4) dihydrochloride is a deuterium labeled Ethane-1,2-diamine.
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- HY-W098607
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PROTAC Linkers
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Cancer
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N1-Benzyl-N1-methylethane-1,2-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W007978A
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S-(-)-2,2-Diamino-1,1-binaphthyl
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Biochemical Assay Reagents
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Others
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(S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-20010
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Drug Intermediate
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Others
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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine is a drug intermediate for synthesis of various active compounds.
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- HY-W037146
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(1R,2R)-N,N'-Bis(phenylmethyl)-1,2-cyclohexanediamine
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Drug Intermediate
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Others
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(1R,2R)-N1,N2-Dibenzylcyclohexane-1,2-diamine ((1R,2R)-N,N'-Bis(phenylmethyl)-1,2-cyclohexanediamine) is a drug intermediate for synthesis of various active compounds.
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- HY-W015248
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PROTAC Linkers
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Cancer
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Hexane-1,6-diamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W016871
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PROTAC Linkers
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Cancer
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Decane-1,10-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W025838
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Drug Intermediate
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Others
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4,5-Dimethylbenzene-1,2-diamine is a substitute for aromatic diamine compound. 4,5-Dimethylbenzene-1,2-diamine act as a bidentate nucleophilic reagent and participates in the palladium (II)-mediated isocyanate addition reaction to construct a diaminocarbene palladium complex with potential catalytic activity .
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- HY-W010634
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PROTAC Linkers
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Cancer
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N-Methylpropane-1,3-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W007732B
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1,4-Diaminocyclohexane
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PROTAC Linkers
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Inflammation/Immunology
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Cyclohexane-1,4-diamine (1,4-Diaminocyclohexane) is a PROTAC Linker and can be used for PROTAC synthesis, such as TYD-68 (HY-173357) .
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- HY-32007A
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Drug Intermediate
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Others
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N1,N1-Dimethylpropane-1,2-diamine dihydrochloride is a drug intermediate for synthesis of various active compounds.
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- HY-42303
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Drug Intermediate
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Others
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2-(Aminomethyl)-N1,N1-dimethylpropane-1,3-diamine trihydrochloride is a drug intermediate for synthesis of various active compounds.
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- HY-76798
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Drug Intermediate
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Others
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N7,N7-Dimethyl-3-m-tolylisoquinoline-1,7-diamine is a drug intermediate for synthesis of various active compounds.
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- HY-173635
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ADC Linker
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Cancer
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Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639) .
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- HY-W009169
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BTDA
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Drug Intermediate
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Others
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Benzophenonetetracarboxylic dianhydride is widely used in the synthesis of high-performance polyimides and other polymer materials. Benzophenonetetracarboxylic dianhydride reacts with various diamine compounds to form oligoimide chains. These oligimide chains can modify graphene oxide (Go) and enhance its properties .
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- HY-W822784
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PROTAC Linkers
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Cancer
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N1-Methylbutane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W012684S
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Ethylenediamine-13C2 dihydrochloride
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Isotope-Labeled Compounds
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Others
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Ethane-1,2-diamine dihydrochloride- 13C2 is the 13C labeled Ethane-1,2-diamine dihydrochloride .
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- HY-W007627R
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o-Phenylenediamine, 4-nitro- (Standard)
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Reference Standards
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4-Nitrobenzene-1,2-diamine (Standard) is the analytical standard of 4-Nitrobenzene-1,2-diamine. This product is intended for research and analytical applications.
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- HY-160899A
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Drug-Linker Conjugates for ADC
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Cancer
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Thailanstatin A cyclohexane diamine formic is an analog of Spliceostatin (HY-16466). Thailanstatin A cyclohexane diamine formic inhibits proliferations of cells N87 (IC50 is 0.33 μM), BT474 (IC50 is 0.34 μM), MDA-MB-361-DYT2 (IC50 is 0.88 μM) and MDA-MB-468 (IC50 is 0.27 μM). Thailanstatin A cyclohexane diamine formic is used as a drug-linker conjugate for ADC molecule .
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- HY-W007978B
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2,2'-Diamino-1,1'-dinaphthyl
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MOFs
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Others
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1,1'-Binaphthyl-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W088621
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PROTAC Linkers
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Cancer
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N1,N4-Dimethylbutane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W017529S
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- HY-W011886S
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Isotope-Labeled Compounds
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Others
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N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9 is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine .
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- HY-W103498
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Biochemical Assay Reagents
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Others
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N4,N4'-Diphenyl-N4,N4'-bis(9-phenyl-3-carbazolyl)biphenyl-4,4'-diamine (Compound HT-01) is a biochemical reagent. N4,N4'-Diphenyl-N4,N4'-bis(9-phenyl-3-carbazolyl)biphenyl-4,4'-diamine can be used in the research of layered semiconductor devices with low-refractive-index organic coatings .
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- HY-W097960
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Biochemical Assay Reagents
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Others
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1,2-Diamino-4,5-dimethoxybenzene hydrochloride is an aromatic diamine that reacts with aldehydes to produce highly fluorescent benzimidazole derivatives.
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- HY-W040196
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Biochemical Assay Reagents
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Others
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1,3-Benzodioxole-5,6-diaminedihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W702995
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1,5-Naphthylene-diamine-d6
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Isotope-Labeled Compounds
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Others
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Naphthalene-1,5-diamine-d6 (1,5-Naphthylene-diamine-d6) is the deuterium labeled Naphthalene-1,5-diamine (HY-W012566).
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- HY-W127840
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- HY-W012566S
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- HY-77873
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Others
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Metabolic Disease
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4,5-Dimethoxybenzene-1,2-diamine 4,5-Dimethoxybenzene-1,2-diamine can be used as a standard for the determination of methyldiacetaldehyde, an intermediate product of glycolysis and a diabetic ketone Biomarkers of acidosis .
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- HY-Y1368S
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- HY-141905S
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- HY-32007
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- HY-W701295
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- HY-W098350
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PROTAC Linkers
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Cancer
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N1,N6-Dimethylhexane-1,6-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W015248S
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Hexamethylenediamine Dihydrochloride-d12
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Isotope-Labeled Compounds
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Others
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Hexane-1,6-diamine dihydrochloride-d12 (Hexamethylenediamine Dihydrochloride-d12) is the deuterium labeled Hexane-1,6-diamine dihydrochloride (HY-W015248).
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- HY-101048
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Bacterial
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Infection
Metabolic Disease
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Synthalin A sulfate is a biguanylated diamine with antibacterial and hypoglycemic properties. Synthalin A sulfate against S. aureus with a MIC of 64 μg/mL .
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- HY-168726
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PROTAC Linkers
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Cancer
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Octane-1,8-diamine-Glycolic acid is a PROTAC linker that can be used to synthesize PROTAC molecules (HY-168725) for research in the cancer .
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- HY-W722305
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Drug Intermediate
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Others
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N1,N4-Di-P-tolylbenzene-1,4-diamine is a chemical intermediate. It acts as a catalyst in various chemical reactions, facilitating the formation of specific molecular structures.
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- HY-W722079
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4-Propylthio-1,2-phenylenediamine-d7
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Isotope-Labeled Compounds
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Others
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4-(Propylthio)benzene-1,2-diamine-d7 (4-Propylthio-1,2-phenylenediamine-d7) is the deuterium labeled 4-(Propylthio)benzene-1,2-diamine (HY-W343702).
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- HY-W090915S
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Isotope-Labeled Compounds
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Others
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N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d12 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine) .
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- HY-W090915S1
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Isotope-Labeled Compounds
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Others
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N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d24 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine) .
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- HY-152408
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Nucleoside Antimetabolite/Analog
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Others
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2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152828
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Nucleoside Antimetabolite/Analog
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Cancer
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1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-163524
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Apoptosis
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Cancer
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NAE-IN-2 (compound III-26) is N2–(1-benzylpiperidin-4-yl)quinazoline-2,4-diamine derivative, and inhibits Cullin1 and Cullin3. NAE-IN-2 inhibits migration and induces cell apoptosis of gastric cancer cells .
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- HY-108497A
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Somatostatin Receptor
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Neurological Disease
Cancer
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L-803087 TFA is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. L-803087 TFA is >280-fold more selective for sst4 receptor than other somatostatin receptors. L-803087 TFA facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice .
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- HY-W131541
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PROTAC Linkers
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Cancer
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tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W012834R
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Tolylene-3,4-diamine (Standard)
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Reference Standards
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3,4-Diaminotoluene (Standard) is the analytical standard of 3,4-Diaminotoluene. This product is intended for research and analytical applications.
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- HY-W104389
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2,2'-Bipyridine-3,3'-diamine
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MOFs
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Others
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[2,2'-Bipyridine]-3,3'-diamine (2,2'-Bipyridine-3,3'-diamine) is a metal-organic framework (MOF).
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- HY-W710638
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- HY-W016750R
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- HY-W017361R
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Reference Standards
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2-Nitrobenzene-1,4-diamine (Standard) is the analytical standard of 2-Nitrobenzene-1,4-diamine. This product is intended for research and analytical applications.
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- HY-W007705R
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Reference Standards
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6-Chloropyrimidine-2,4-diamine (Standard) is the analytical standard of 6-Chloropyrimidine-2,4-diamine. This product is intended for research and analytical applications.
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- HY-W239318
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PROTAC Linkers
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Cancer
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N1-Methylpentane-1,5-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W703049
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- HY-W129440R
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Reference Standards
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N6-Cyclopropyl-9H-purine-2,6-diamine (Standard) is the analytical standard of N6-Cyclopropyl-9H-purine-2,6-diamine. This product is intended for research and analytical applications.
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- HY-W052889R
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6-Ethyl-pyrimidine-2,4-diyldiamine (Standard)
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Reference Standards
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6-Ethylpyrimidine-2,4-diamine (Standard) is the analytical standard of 6-Ethylpyrimidine-2,4-diamine. This product is intended for research and analytical applications.
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- HY-W376544
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PROTAC Linkers
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Cancer
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N1,N4-dimethylcyclohexane-1,4-diamine is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-169529S
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- HY-W243991
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MOFs
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Others
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2,2'-Dimethyl-[1,1'-binaphthalene]-4,4'-diamine is a metal-organic framework (MOF).
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- HY-W243992
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MOFs
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Others
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2,2'-Diphenyl-[1,1'-binaphthalene]-4,4'-diamine is a metal-organic framework (MOF).
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- HY-W003372R
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Reference Standards
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(S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine (Standard) is the analytical standard of (S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine. This product is intended for research and analytical applications.
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- HY-W456462
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MOFs
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Others
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N2,N7-Bis(diphenylmethylene)phenazine-2,7-diamine is a metal-organic framework (MOF).
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- HY-W1049865
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MOFs
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Others
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1H,1'H-[4,4'-Bipyrazole]-3,3'-diamine is a metal-organic framework (MOF).
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- HY-W080687
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2,4,5,6-Tetrafluorobenzene-1,3-diamine
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Biochemical Assay Reagents
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Cancer
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1,3-Diaminotetrafluorobenzene (2,4,5,6-Tetrafluorobenzene-1,3-diamine) (Compound 48) is a carcinogenic aniline with carcinogenic activity .
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- HY-W075528
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MOFs
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Others
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N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine is a metal-organic framework (MOF).
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- HY-W075527
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MOFs
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Others
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N1,N1-Bis(pyridin-2-ylmethyl)ethane-1,2-diamine is a metal-organic framework (MOF).
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- HY-W075531
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MOFs
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Others
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N1,N3-Di(pyridin-2-yl)benzene-1,3-diamine is a metal-organic framework (MOF).
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- HY-W112117
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MOFs
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Others
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N1,N5-Bis(pyridin-4-ylmethylene)naphthalene-1,5-diamine is a metal-organic framework (MOF).
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- HY-W856336
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MOFs
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Others
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N1,N2-Bis(pyridin-4-ylmethyl)ethane-1,2-diamine is a metal-organic framework (MOF).
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- HY-W112118
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MOFs
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Others
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N1,N4-Bis((pyridin-4-yl)-methylene)benzene-1,4-diamine is a metal-organic framework (MOF).
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- HY-W015829S
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Tetramethylpropylenediamine-d18
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Isotope-Labeled Compounds
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Others
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N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18 is the deuterium labeled N1,N1,N3,N3-Tetramethylpropane-1,3-diamine .
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- HY-W075525
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MOFs
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Others
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N1,N1,N3,N3-Tetrakis(pyridin-2-ylmethyl)propane-1,3-diamine is a metal-organic framework (MOF).
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- HY-W249347
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MOFs
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Others
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N1,N1,N4,N4-Tetra(pyridin-2-yl)benzene-1,4-diamine is a metal-organic framework (MOF).
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- HY-W456294
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MOFs
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Others
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N1,N1,N3,N3-Tetra(pyridin-4-yl)benzene-1,3-diamine is a metal-organic framework (MOF).
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- HY-W075532
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MOFs
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Others
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N1-Benzyl-N1,N3,N3-tris(pyridin-2-ylmethyl)propane-1,3-diamine is a metal-organic framework (MOF).
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- HY-W856350
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MOFs
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Others
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N2,N6-Dimethyl-N2,N6-di(pyridin-2-yl)pyridine-2,6-diamine is a metal-organic framework (MOF).
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- HY-W243984
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MOFs
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Others
|
|
N4,N4,N4',N4'-Tetra(pyridin-2-yl)-[1,1'-biphenyl]-4,4'-diamine is a metal-organic framework (MOF).
|
-
- HY-W1049869
-
|
|
MOFs
|
Others
|
|
N4,N4,N4',N4'-tetra(pyridin-4-yl)-[1,1'-biphenyl]-4,4'-diamine is a metal-organic framework (MOF).
|
-
- HY-W112124
-
|
|
MOFs
|
Others
|
|
N1-(Pyridin-4-ylmethyl)-N2,N2-bis(2-((pyridin-4-ylmethyl)amino)ethyl)ethane-1,2-diamine is a metal-organic framework (MOF).
|
-
- HY-W249343
-
|
|
MOFs
|
Others
|
|
N4,N4,N4',N4'-Tetrakis(4-(pyridin-4-yl)phenyl)-[1,1'-biphenyl]-4,4'-diamine is a metal-organic framework (MOF).
|
-
- HY-W456312
-
|
|
MOFs
|
Others
|
|
(1R,2R)-rel-N1,N2-Dimethyl-N1,N2-bis(pyridin-2-ylmethyl)cyclohexane-1,2-diamine is a metal-organic framework (MOF).
|
-
- HY-W249348
-
|
|
MOFs
|
Others
|
|
N1,N1,N4,N4-Tetrakis(4-(4H-1,2,4-triazol-4-yl)phenyl)benzene-1,4-diamine is a metal-organic framework (MOF).
|
-
- HY-W249119
-
|
|
MOFs
|
Others
|
|
2-(Bis(4-chlorophenyl)methyl)-N4-(3-(bis(4-chlorophenyl)methyl)-4-(dimethylamino)phenyl)-N1,N1-dimethylbenzene-1,4-diamine is a metal-organic framework (MOF).
|
-
- HY-W112131
-
|
3,6-Bis[N,N-bis(4-methoxyphenyl)amino]-9H-carbazole
|
MOFs
|
Others
|
|
N,N,N',N'-Tetrakis(4-methoxyphenyl)-9H-carbazole-3,6-diamine(3,6-Bis[N,N-bis(4-methoxyphenyl)amino]-9H-carbazole) is a metal-organic framework (MOF).
|
-
- HY-W075526
-
|
1,4-Bis[bis(4-pyridinyl)amino]benzene
|
MOFs
|
Others
|
|
N1,N1,N4,N4-Tetra(pyridin-4-yl)benzene-1,4-diamine(1,4-Bis[bis(4-pyridinyl)amino]benzene) is a metal-organic framework (MOF).
|
-
- HY-W1050064
-
4-(5,5-Difluoro-1,3,7,9-tetramethyl-5H-4lambda4,5lambda4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzene-1,2-diamine
|
MOFs
|
Others
|
|
4-(5,5-Difluoro-1,3,7,9-tetramethyl-5H-4lambda4,5lambda4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzene-1,2-diamine is a metal-organic framework (MOF).
|
-
- HY-W714205S
-
-
- HY-108497R
-
|
|
Reference Standards
Somatostatin Receptor
|
Neurological Disease
Cancer
|
|
L-803087 (Standard) is the analytical standard of L-803087 (HY-108497). This product is intended for research and analytical applications. L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. L-803087 is >280-fold higher than other somatostatin receptors. L-803087 facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice .
|
-
- HY-P2890D
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Laccase, Agaricus bisporus (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.
|
-
- HY-P2890H
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Laccase, Pleurotus ostreatus (mushroom) (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.
|
-
- HY-P2890I
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Laccase, White rot fungi (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.
|
-
- HY-W021358
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N,N,N′,N′-Tetramethyl-p-phenylenediamine is an electron-donating aromatic diamine with a low ionization potential. N,N,N′,N′-Tetramethyl-p-phenylenediamine is a classic electron donor model compound for photochemical electron transfer studies .
|
-
- HY-P2890B
-
|
|
Fungal
|
Metabolic Disease
|
|
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.
|
-
- HY-P2890C
-
|
|
Fungal
|
Metabolic Disease
|
|
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.
|
-
- HY-B1041A
-
|
Pimagedine; GER-11free base ; Aminoguanidinium
|
NO Synthase
Apoptosis
|
Endocrinology
|
|
Aminoguanidine (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine has antioxidant properties. Aminoguanidine can be used in diabetic nephropathy research .
|
-
- HY-B1041R
-
|
Pimagedine hydrochloride (Standard); GER-11 (Standard); Aminoguanidinium chloride (Standard)
|
NO Synthase
Apoptosis
Reference Standards
|
Endocrinology
|
|
Aminoguanidine (hydrochloride) (Standard) is the analytical standard of Aminoguanidine (hydrochloride). This product is intended for research and analytical applications. Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research .
|
-
- HY-W076339R
-
-
- HY-W128350R
-
|
6-Pyrrolidin-1-ylpyrimidine-2,4-diamine (Standard)
|
Reference Standards
|
|
|
2,4-Diamino-6-piperidinopyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-piperidinopyrimidine. This product is intended for research and analytical applications.
|
-
- HY-B1041
-
|
Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride
|
NO Synthase
Apoptosis
ERK
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .
|
-
- HY-Y0400S
-
|
N,N-diprop-2-en-1-ylethane-1,2-diamine
|
Isotope-Labeled Compounds
|
Others
|
|
2-Bromoethylammonium-d4 bromide is the deuterium labeled 2-Bromoethylammonium bromide[1].
|
-
- HY-P2888A
-
|
BOD, bacillus cereus
|
Endogenous Metabolite
|
Metabolic Disease
|
Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors .
|
-
- HY-P2888C
-
|
BOD, Bacillus pumilus
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors .
|
-
- HY-Y0047
-
|
Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .
|
-
- HY-B1041AS
-
|
Pimagedine-13C, 15N4; GER-11free base-13C, 15N4; Aminoguanidinium-13C, 15N4
|
Isotope-Labeled Compounds
NO Synthase
Apoptosis
|
Endocrinology
|
|
Aminoguanidine- 13C, 15N4 (Pimagedine- 13C, 15N4) is the 13C- and 15N-labeled Aminoguanidine (HY-B1041A). Aminoguanidine (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine has antioxidant properties. Aminoguanidine can be used in diabetic nephropathy research .
|
-
- HY-150667S
-
|
N6-(3-Methoxy-d3-phenyl)-7H-purine-2,6-diamine
|
Isotope-Labeled Compounds
|
Others
|
|
2-Amino-6-(3-methoxy-anilino)purine-d3 is the deuterium labeled 2-Amino-6-(3-methoxy-anilino)purine .
|
-
- HY-W053507
-
|
3-Methylbenzeneacetic acid
|
Drug Metabolite
Drug Intermediate
|
Others
|
|
m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules .
|
-
- HY-173703
-
|
|
Topoisomerase
Drug Intermediate
|
Cancer
|
|
β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is a topoisomerase I inhibitor. β-Glu-PAB(CH2NH2)-Exatecan binds to the topoisomerase I-DNA complex to prevent DNA strand reconnection, thereby inducing DNA breakage and cell apoptosis. β-Glu-PAB(CH2NH2)-Exatecan can be specifically cleaved by β-glucuronidase highly expressed in the tumor microenvironment to release Exatecan for cytotoxic effect. β-Glu-PAB(CH2NH2)-Exatecan is also an intermediate of Mal((3S,3aR,6S,6aR) -hexahydrofuro [3, 2-B]furan-3,6-diamine-PEG12)-β -Glu-Pab-Exatecan. β-Glu-PAB(CH2NH2)-Exatecan is promising for research of cancers .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W017529
-
|
2-Chloro-4,6-diamino-1,3,5-triazine
|
Biochemical Assay Reagents
|
|
6-Chloro-1,3,5-triazine-2,4-diamine (2-Chloro-4,6-diamino-1,3,5-triazine) is a versatile synthetic organic compound that can be used as a catalyst.
|
-
- HY-W115752
-
|
diamine sulfate (99%)
|
Biochemical Assay Reagents
|
|
Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-Km ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP + toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease .
|
-
- HY-W013631
-
|
|
Biochemical Assay Reagents
|
|
7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007978A
-
|
S-(-)-2,2-Diamino-1,1-binaphthyl
|
Biochemical Assay Reagents
|
|
(S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W040196
-
|
|
Biochemical Assay Reagents
|
|
1,3-Benzodioxole-5,6-diaminedihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127840
-
|
1,1,2,2-tetradeuterioethane-1,2-diamine-d4
|
Biochemical Assay Reagents
|
|
Ethylene-d4-diamine is the deuterium labeled Ethylene-diamine .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W012684S1
-
|
|
|
Ethane-1,2-diamine-d4 (Ethylenediamine-d4) dihydrochloride is a deuterium labeled Ethane-1,2-diamine.
|
-
-
- HY-W012684S
-
|
|
|
Ethane-1,2-diamine dihydrochloride- 13C2 is the 13C labeled Ethane-1,2-diamine dihydrochloride .
|
-
-
- HY-W017529S
-
|
|
|
6-Chloro-1,3,5-triazine-2,4-diamine- 13C3 is the 13C3 labeled 6-Chloro-1,3,5-triazine-2,4-diamine.
|
-
-
- HY-W011886S
-
|
|
|
N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9 is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine .
|
-
-
- HY-W702995
-
|
|
|
Naphthalene-1,5-diamine-d6 (1,5-Naphthylene-diamine-d6) is the deuterium labeled Naphthalene-1,5-diamine (HY-W012566).
|
-
-
- HY-W127840
-
|
|
|
Ethylene-d4-diamine is the deuterium labeled Ethylene-diamine .
|
-
-
- HY-W012566S
-
|
|
|
Naphthalene-1,5-diamine- 15N2 is the 15N labeled Naphthalene-1,5-diamine .
|
-
-
- HY-Y1368S
-
|
|
|
Pyridine-d3-2,3-diamine is the deuterium labeled 2,3-Diaminopyridine (HY-Y1368).
|
-
-
- HY-141905S
-
|
|
|
Isophorone Diamine- 13C, 15N2 is the 13C and 15N labeled Isophorone Diamine .
|
-
-
- HY-W701295
-
|
|
|
N1-(Methyl-d3)-4-nitrobenzene-1,2-diamine is the deuterium labeled N1-Methyl-4-nitrobenzene-1,2-diamine (HY-W042177).
|
-
-
- HY-W015248S
-
|
|
|
Hexane-1,6-diamine dihydrochloride-d12 (Hexamethylenediamine Dihydrochloride-d12) is the deuterium labeled Hexane-1,6-diamine dihydrochloride (HY-W015248).
|
-
-
- HY-W722079
-
|
|
|
4-(Propylthio)benzene-1,2-diamine-d7 (4-Propylthio-1,2-phenylenediamine-d7) is the deuterium labeled 4-(Propylthio)benzene-1,2-diamine (HY-W343702).
|
-
-
- HY-W090915S
-
|
|
|
N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d12 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine) .
|
-
-
- HY-W090915S1
-
|
|
|
N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d24 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine) .
|
-
-
- HY-150667S
-
|
|
|
2-Amino-6-(3-methoxy-anilino)purine-d3 is the deuterium labeled 2-Amino-6-(3-methoxy-anilino)purine .
|
-
-
- HY-W710638
-
|
|
|
Pentane-1,5-diamine- 15N2 dihydrochloride is the 15N-labeled Pentane-1,5-diamine dihydrochloride (HY-W016750). Pentane-1,5-diamine dihydrochloride is an endogenous metabolite.
|
-
-
- HY-W703049
-
|
|
|
N1,N4-dimethylbenzene-1,4-diamine-d6 is the deuterium labeled N1,N4-dimethylbenzene-1,4-diamine.
|
-
-
- HY-169529S
-
|
|
|
N3-Tritylpyridine-2,3-diamine-d3 is the deuterium labeled WAY-329340 (HY-169529).
|
-
-
- HY-W015829S
-
|
|
|
N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18 is the deuterium labeled N1,N1,N3,N3-Tetramethylpropane-1,3-diamine .
|
-
-
- HY-W714205S
-
|
|
|
Desethyl terbumeton-d3 is deuterium labeled N2-(Tert-butyl)-6-methoxy-1,3,5-triazine-2,4-diamine .
|
-
-
- HY-Y0400S
-
|
|
|
2-Bromoethylammonium-d4 bromide is the deuterium labeled 2-Bromoethylammonium bromide[1].
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-152408
-
|
|
|
Nucleoside Analogs
|
|
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152828
-
|
|
|
Nucleoside Analogs
|
|
1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
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