7H-Purine-2,6-diamine
Based on 1 Customer Validation
7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 1904-98-9
- Formula: C5H6N6
- Molecular Weight:150.14
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-HSB-2 | CC50 |
>20 μM
Compound: DAP
|
Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay
Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay
|
[PMID: 22607883] |
| HFF | CC50 |
>300 μM
Compound: DAP
|
Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining
Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining
|
[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: DAP
|
Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay
Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay
|
[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: DAP
|
Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
|
[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: DAP
|
Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
|
[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: DAP
|
Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining
Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining
|
[PMID: 22607883] |
| MOLT-3 | CC50 |
>20 μM
Compound: DAP
|
Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay
Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay
|
[PMID: 22607883] |
| MOLT-3 | IC50 |
16 μM
Compound: DAP
|
Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay
Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay
|
[PMID: 22607883] |
| Oocyte | IC50 |
>100 μM
Compound: 2
|
Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentration tested)
Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentration tested)
|
[PMID: 9046330] |
2,6-Diaminopurine is a compound used to study leukemia.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1904-98-9
-
Appearance Solid
-
Molecular Weight 150.14
-
Formula C5H6N6
-
Color Off-white to yellow
-
SMILES
NC1=NC(N)=C2NC=NC2=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 58.33 mg/mL (388.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (245 KB)
-
SDS (558 KB)
- English - EN (558 KB)
- Français - FR (558 KB)
- Deutsch - DE (558 KB)
- Norwegian - NO (558 KB)
- Español - ES (558 KB)
- Swedish - SV (558 KB)
- Italian - IT (558 KB)
- Korean - KR (558 KB)
- Portuguese - PT (558 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.6605 mL | 33.3023 mL | 66.6045 mL | 166.5113 mL |
| 5 mM | 1.3321 mL | 6.6605 mL | 13.3209 mL | 33.3023 mL | |
| 10 mM | 0.6660 mL | 3.3302 mL | 6.6605 mL | 16.6511 mL | |
| 15 mM | 0.4440 mL | 2.2202 mL | 4.4403 mL | 11.1008 mL | |
| 20 mM | 0.3330 mL | 1.6651 mL | 3.3302 mL | 8.3256 mL | |
| 25 mM | 0.2664 mL | 1.3321 mL | 2.6642 mL | 6.6605 mL | |
| 30 mM | 0.2220 mL | 1.1101 mL | 2.2202 mL | 5.5504 mL | |
| 40 mM | 0.1665 mL | 0.8326 mL | 1.6651 mL | 4.1628 mL | |
| 50 mM | 0.1332 mL | 0.6660 mL | 1.3321 mL | 3.3302 mL | |
| 60 mM | 0.1110 mL | 0.5550 mL | 1.1101 mL | 2.7752 mL | |
| 80 mM | 0.0833 mL | 0.4163 mL | 0.8326 mL | 2.0814 mL | |
| 100 mM | 0.0666 mL | 0.3330 mL | 0.6660 mL | 1.6651 mL |