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By Targets:	Amyloid-β (1) Antibiotic (2) Bacterial (3) Fluorescent Dye (1) IFNAR (1) Interleukin Related (2) Itk (1) Reference Standards (1) SARS-CoV (2) TNF Receptor (1) Trk Receptor (1)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1150

Clofoctol 1 Publications Verification	Bacterial SARS-CoV Antibiotic	Infection Cancer
Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

HY-B1150R

Clofoctol (Standard)	Reference Standards Bacterial SARS-CoV Antibiotic	Infection Cancer
Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

HY-182335

PF-07245303	Itk Trk Receptor Interleukin Related IFNAR	Inflammation/Immunology
PF-07245303 is a ITK/TRK inhibitor. PF-07245303 reduces the production of inflammatory cytokines such as IL-4 and IFNγ, and inhibits the phosphorylation of PLCγ1. PF-07245303 inhibits nerve growth factor-induced basophil activation and the phosphorylation of TRKA. PF-07245303 reduces oxazolone-induced ear swelling in mouse ear tissues. PF-07245303 is applicable to research related to atopic dermatitis .

HY-183367

Anti-inflammatory agent 115	TNF Receptor Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 115 is a potent anti-inflammatory agent. Anti-inflammatory agent 115 reduces secretion of myeloperoxidase (MPO), TNF-α, IL-1β, and IL-6. Anti-inflammatory agent 115 decreases ear tissue thickness and neutrophil infiltration in 12-O-tetradecanoylphorbol-13-acetate (TPA) (HY-18739)-induced topical edema in mice. Anti-inflammatory agent 115 can be used for the research of inflammatory diseases .

HY-D3192

CDy11	Fluorescent Dye Bacterial Amyloid-β	Infection
CDy11 is a fluorescent probe and amyloid-binding dye (λ_ex=590 nm; λ_em=612 nm), with a K_a of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .

Cat. No.	Product Name	Type

HY-D3192

CDy11	Fluorescent Dyes
CDy11 is a fluorescent probe and amyloid-binding dye (λ_ex=590 nm; λ_em=612 nm), with a K_a of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .

CDy11

Fluorescent Dyes

CDy11 is a fluorescent probe and amyloid-binding dye (λ_ex=590 nm; λ_em=612 nm), with a K_a of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .

Cat. No.	Product Name

HY-K0536

*Mouse Tissue* Direct PCR Kit – Pro (with Dye)**
MCE Mouse Tissue Direct PCR Kit – Pro (with Dye) is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

Mouse Tissue Direct PCR Kit – Pro (with Dye)

MCE Mouse Tissue Direct PCR Kit – Pro (with Dye) is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

HY-K0534

*Mouse Tissue* Direct PCR Kit (with Dye)**
MCE Mouse Tissue Direct PCR Kit (with Dye) is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

Mouse Tissue Direct PCR Kit (with Dye)

MCE Mouse Tissue Direct PCR Kit (with Dye) is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

HY-K0535

*Mouse Tissue* Direct PCR Plus Kit**
MCE Mouse Tissue Direct PCR Plus Kit is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

Mouse Tissue Direct PCR Plus Kit

MCE Mouse Tissue Direct PCR Plus Kit is specifically designed for direct PCR amplification from tissue samples. It enables rapid, one-step release of genomic DNA from various mouse tissues (such as tail, ear, toe, and muscle), which can be directly used for downstream PCR amplification and analysis without the need for conventional DNA extraction and purification steps, thereby significantly simplifying the experimental workflow.

HY-K0005

*Mouse Tissue* Lysis Buffer**
MCE Mouse Tissue Lysis Buffer formulated with a highly efficient lysis buffer system, enabling rapid disruption of various mouse tissue samples (e.g., tail, ear, toe, muscle) and efficient release of genomic DNA. The lysate can be directly used as a template in PCR reactions without the need for additional extraction or purification steps, ensuring a simple and streamlined workflow.

HY-K0538

*Animal Tissue* Direct PCR Kit (with Dye)**
MCE Animal Tissue Direct PCR Kit (with Dye) is specifically designed for direct amplification from a variety of animal tissue samples. It enables rapid release of genomic DNA from animal tissues (such as insect legs/wings, mouse tails, ears, toes, skin, and internal organs) in a single step, allowing the lysate to be used directly for downstream PCR amplification without the need for conventional DNA extraction and purification procedures, thereby significantly simplifying the workflow.

Animal Tissue Direct PCR Kit (with Dye)

MCE Animal Tissue Direct PCR Kit (with Dye) is specifically designed for direct amplification from a variety of animal tissue samples. It enables rapid release of genomic DNA from animal tissues (such as insect legs/wings, mouse tails, ears, toes, skin, and internal organs) in a single step, allowing the lysate to be used directly for downstream PCR amplification without the need for conventional DNA extraction and purification procedures, thereby significantly simplifying the workflow.

Clofoctol 1 Publications Verification	Classification of Application Fields Antibacterial Disease Research Other Antibiotics Infection Monophenols Microorganisms Antibiotics Phenols Antiviral Anticancer Disease Research Fields Source Classification	Bacterial SARS-CoV Antibiotic
Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

Clofoctol (Standard)	Structural Classification Monophenols Microorganisms Antibiotics Phenols Antiviral Antibacterial Disease Research Anticancer Other Antibiotics Source Classification	Reference Standards Bacterial SARS-CoV Antibiotic
Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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ear tissues

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