55 Results for "

enkephalin

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "enkephalin" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P0073
CAS No.: 58569-55-4
Synonyms: Met-enkephalin; Methionine enkephalin; Metenkefalin
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease Cancer

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
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2
2 Cited Publications
Cat. No.: HY-P0288
CAS No.: 58822-25-6
Synonyms: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin
[Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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1
1 Cited Publications
Cat. No.: HY-105343
CAS No.: 63631-40-3
Purity:  99.92%
Synonyms: [D-Ala2, D-Leu5]-enkephalin; DADLE
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

BW-180C ([D-Ala2, D-Leu5]-Enkephalin; DADLE) is an δ opioid receptor (DOR) agonist, which belongs to the enkephalin family. Neuroprotective agent. BW-180C reversibly inhibits cellular transcription in neurons without causing cell injury .
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1
1 Cited Publications
Cat. No.: HY-P4270
CAS No.: 67368-29-0
Target:  

Neprilysin

Research Areas:  

Neurological Disease

Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease .
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Cat. No.: HY-W345510
CAS No.: 864084-88-8
Target:  

Neprilysin

Research Areas:  

Neurological Disease

Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission .
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Cat. No.: HY-P0098
CAS No.: 64963-01-5
[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.
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Cat. No.: HY-P1701
CAS No.: 74135-04-9
Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for Enkephalin receptors .
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Cat. No.: HY-P1470
CAS No.: 60117-24-0
Synonyms: Leu-enkephalin amide
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[Leu5]-Enkephalin, amide is a δ opioid receptor agonist.
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Cat. No.: HY-P3513
CAS No.: 77739-21-0
Target:  

ERK MMP

Research Areas:  

Neurological Disease

β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9 .
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Cat. No.: HY-P1467A
CAS No.: 2918768-28-0
Synonyms: 5-Methionine-enkephalin amide TFA
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[Met5]-Enkephalin, amide TFA is an agonist for δ opioid receptors as well as putative ζ ζ opioid receptors.
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Cat. No.: HY-118120
CAS No.: 77482-44-1
Synonyms: 2-Guanidinoethylmercaptosuccinic acid
Target:  

Carboxypeptidase

Research Areas:  

Neurological Disease

GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-W048697
CAS No.: 201532-01-6
Research Areas:  

Others

Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
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Cat. No.: HY-P3546
CAS No.: 88373-72-2
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[DPen2, Pen5] Enkephalin is a δ-opioid receptor selective analog of [Leu5]-Enkephalin (HY-P0288) .
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Cat. No.: HY-P2626
CAS No.: 61370-87-4
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[D-Ala2]-Met-Enkephalin, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalin inhibits ACh-induced and suckling-induced oxytocin (OT) release .
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Cat. No.: HY-117702
CAS No.: 135949-60-9
RB 101 is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor. RB 101 blocks enkephalin breakdown, elevates extracellular enkephalin levels and activate δ-opioid receptor and dopamine D1 receptor. RB 101 can be used for the research of pain, depressive syndromes, and diabetic neuropathy .
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Cat. No.: HY-P1044
CAS No.: 137201-62-8
Synonyms: LVV-hemorphin-4
Target:  

Carboxypeptidase

Research Areas:  

Neurological Disease

Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .
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Cat. No.: HY-P1044A
CAS No.: 2828433-21-0
Synonyms: LVV-hemorphin-4 TFA
Target:  

Angiotensin Receptor

Research Areas:  

Neurological Disease

Spinorphin TFA is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect .
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Cat. No.: HY-19876
CAS No.: 935481-06-4
Synonyms: Debio-0827
PL37 (Debio-0827) is an orally active, blood-brain barrier permeable dual enkephalinase inhibitor. PL37 inhibits aminopeptidase N, neprilysin, and metalloproteases, thereby blocking the degradation of endogenous enkephalins, elevating enkephalin levels, and activating peripheral μ- and δ-opioid receptors. PL37 induces mitochondrial dysfunction, mitophagy, and apoptosis, inhibits endothelial cell proliferation, migration, invasion, and tube formation, and suppresses hemangioma tumor growth and angiogenesis. PL37 can be used in research related to peripheral neuropathic pain, osteosarcoma-induced hyperalgesia, painful diabetic neuropathy, migraine, bone cancer pain, neuroinflammatory pain, and infantile hemangioma .
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Cat. No.: HY-P3962
CAS No.: 34783-35-2
Research Areas:  

Endocrinology

[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin .
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