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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
exotoxin
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "exotoxin" in MCE Product Catalog:
7
7
Cat. No.: HY-112779
CAS No.: 70323-44-3
Target:
Research Areas:
Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins .
Cat. No.: HY-P1698
CAS No.: 1447799-33-8
Synonyms: AB-103
Research Areas:
Cat. No.: HY-115501
CAS No.: 1370281-06-3
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(E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research .
Cat. No.: HY-P991550
CAS No.: 505393-48-6
Cat. No.: HY-P2455
CAS No.: 137856-41-8
Synonyms: Listeriolysin O (91-99)
Target:
Research Areas:
Cat. No.: HY-P4984
CAS No.: 137593-46-5
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Cat. No.: HY-169430
CAS No.: 3038861-74-1
Target:
AGU654 (Compound 44) is a selective mPGES-1 inhibitor with an IC50 of 2.9 nM against mPGES-1. AGU654 inhibits mPGES-1 to block the pathway converting arachidonic acid into prostaglandin E2 (PGE2) by COX-1/2, thereby alleviating inflammatory responses, pain, and fever. In activated human monocyte-derived macrophages and human whole blood models, AGU654 selectively suppresses bacterial exotoxin-induced PGE2 production while preserving the production of other prostaglandins. In guinea pig models, AGU654 significantly alleviates fever, inflammation, and inflammatory pain, exhibiting excellent anti-inflammatory, analgesic, and antipyretic effects. AGU654 holds promise as a strategy for studying inflammatory diseases and pain .
Cat. No.: HY-P990708
CAS No.: 1236019-35-4
Synonyms: MDNA55; NBI-3001; PRX-321
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Cat. No.: HY-P1698B
Synonyms: AB-103 TFA
Research Areas:
Cat. No.: HY-P72072
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Streptopain; EC:3.4.22.10; exotoxin type B; Group A streptococcal cysteine protease; Streptococcal cysteine proteinase; Streptococcal cysteine proteinase; SPE B; Streptococcus peptidase A; SPP; speB
Cat. No.: HY-P704245
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Streptopain; EC:3.4.22.10; exotoxin type B; Group A streptococcal cysteine protease; Streptococcal cysteine proteinase; Streptococcal cysteine proteinase; SPE B; Streptococcus peptidase A; SPP; speB
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
