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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
79 Results for "
fluorinated
" in MedChemExpress (MCE) Product Catalog:
Products (79)
79 Results for "fluorinated" in MCE Product Catalog:
111
Research Areas:
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
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5 Cited Publications
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ONC212, a fluorinated-ONC201 analogue, is a promising anti-cancer agent and also a selective agonist of GPR132. ONC212 also induces apoptosis .
3
3 Cited Publications
Synonyms: 5-Fluorocytosine; NSC 103805; Ro 2-9915
Target:
Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
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Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. Desonide can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis .
1
1 Cited Publications
Cat. No.: HY-W039442
CAS No.: 64183-27-3
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2′-Deoxy-2′-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
1
1 Cited Publications
Cat. No.: HY-B0983
CAS No.: 13609-67-1
Synonyms: Cortisol 17-butyrate; Hydrocortisone butyrate
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Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid for use in psoriasis, eczema, and other inflammatory dermatoses. Hydrocortisone 17-butyrate inhibits granuloma formation in rats. Hydrocortisone 17-butyrate can induce vasoconstriction .
1
1 Cited Publications
Cat. No.: HY-W127832
CAS No.: 123148-15-2
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Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .
Cat. No.: HY-W127717
CAS No.: 51142-49-5
Synonyms: Perfluoro-compound FC-40
Cat. No.: HY-21179
CAS No.: 27607-77-8
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Trimethylsilyl trifluoromethylsulfonate is a metal-free catalyst. Trimethylsilyl trifluoromethylsulfonate can be used for the synthesis of biologically active fluorinated heterocyclic compounds .
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SulfoxFluor is a fluorinated sulfoximine compound that can be used in the rapid deoxyfluorination and selective deoxyazidation reactions of various alcohols. SulfoxFluor is characterized by high reactivity, rapid reaction, simple operation, easy scale-up, and high selectivity .
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1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
Cat. No.: HY-W075766
CAS No.: 10028-18-9
Synonyms: Nickel difluoride
Cat. No.: HY-32884
CAS No.: 193353-34-3
Synonyms: fluorinated polymer; Fluoropolymer; PTFE; Polytetrafluoroethylene
Cat. No.: HY-W002291
CAS No.: 1132-68-9
Synonyms: 4-Fluoro-L-phenylalanine
Cat. No.: HY-32887
CAS No.: 156545-07-2
Cat. No.: HY-W050049
CAS No.: 122111-01-7
Cat. No.: HY-W021482
CAS No.: 681128-50-7
Research Areas:
Synonyms: 5-Fluorocytosine (Standard); NSC 103805 (Standard); Ro 2-9915 (Standard)
Target:
Flucytosine (Standard) is the analytical standard of Flucytosine. This product is intended for research and analytical applications. Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
