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Results for "

fluorinated

" in MedChemExpress (MCE) Product Catalog:

72

Inhibitors & Agonists

1

Fluorescent Dyes

15

Biochemical Assay Reagents

4

Peptides

2

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1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0069
    Fludarabine
    Maximum Cited Publications
    106 Publications Verification

    F-ara-A; NSC 118218

    		 Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis Cancer
    Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
    Fludarabine
  • HY-B0139
    Flucytosine
    3 Publications Verification

    5-Fluorocytosine; NSC 103805; Ro 2-9915

    		 Fungal Antibiotic Infection Cancer
    Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
    Flucytosine
  • HY-111343
    ONC212
    5 Publications Verification

    		 Apoptosis Endocrinology Cancer
    ONC212, a fluorinated-ONC201 analogue, is a promising anti-cancer agent and also a selective agonist of GPR132. ONC212 also induces apoptosis .
    ONC212
  • HY-15234
    Fluticasone furoate

    		Glucocorticoid Receptor Inflammation/Immunology
    Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .
    Fluticasone furoate
  • HY-B0248
    Desonide
    2 Publications Verification

    		 Glucocorticoid Receptor Huntingtin Apoptosis Neurological Disease Inflammation/Immunology
    Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. Desonide can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis .
    Desonide
  • HY-W127717
    Fluorinert FC-40

    Perfluoro-compound FC-40

    		 Biochemical Assay Reagents Others
    Fluorinert FC-40 is a non-conductive liquid containing a mixture of fluorinated compounds. It is commonly used as a cooling and heat transfer fluid in electronics, especially in high-performance computer systems and electronic components that generate a lot of heat. Fluorinert FC-40 has various properties that make it ideal for these applications, including its low viscosity, high thermal stability and excellent dielectric strength. In addition, it can be used as an inert solvent in chemical reactions and a lubricant in mechanical systems.
    Fluorinert FC-40
  • HY-W039442
    2′-Deoxy-2′-fluoroadenosine
    1 Publications Verification

    		 Nucleoside Antimetabolite/Analog Infection Cancer
    2′-Deoxy-2′-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
    2′-Deoxy-2′-fluoroadenosine
  • HY-21179
    Trimethylsilyl trifluoromethylsulfonate

    		Biochemical Assay Reagents Others
    Trimethylsilyl trifluoromethylsulfonate is a metal-free catalyst. Trimethylsilyl trifluoromethylsulfonate can be used for the synthesis of biologically active fluorinated heterocyclic compounds .
    Trimethylsilyl trifluoromethylsulfonate
  • HY-B0983
    Hydrocortisone 17-butyrate
    1 Publications Verification

    Cortisol 17-butyrate; Hydrocortisone butyrate

    		 Adrenergic Receptor Inflammation/Immunology Endocrinology
    Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid for use in psoriasis, eczema, and other inflammatory dermatoses. Hydrocortisone 17-butyrate inhibits granuloma formation in rats. Hydrocortisone 17-butyrate can induce vasoconstriction .
    Hydrocortisone 17-butyrate
  • HY-132978
    SulfoxFluor

    		Biochemical Assay Reagents Others
    SulfoxFluor is a fluorinated sulfoximine compound that can be used in the rapid deoxyfluorination and selective deoxyazidation reactions of various alcohols. SulfoxFluor is characterized by high reactivity, rapid reaction, simple operation, easy scale-up, and high selectivity .
    SulfoxFluor
  • HY-32126
    1-Fluoronaphthalene

    		Drug Intermediate Others
    1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene
  • HY-W075766
    Nickel(II) fluoride

    Nickel difluoride

    		 Biochemical Assay Reagents Others
    Nickel(II) fluoride (Nickel difluoride) is a fluorinating agent and catalyst suitable for surface treatment of aluminum profiles and the production of inks, fluorescent lamps, and organic synthesis. Nickel(II) fluoride is a kind of biological materials or organic compounds that are widely used in life science research .
    Nickel(II) fluoride
  • HY-32884
    2,5-Difluorophenylboronic acid

    		Drug Intermediate Others
    2,5-Difluorophenylboronic acid is a phenylboronic acid substituted with 2,5-difluorine groups. 2,5-Difluorophenylboronic acid serves as an organic synthesis intermediate belonging to the fluorinated phenylboronic acid class .
    2,5-Difluorophenylboronic acid
  • HY-109534
    Poly(tetrafluoroethylene)

    fluorinated polymer; Fluoropolymer; PTFE; Polytetrafluoroethylene

    		 Biochemical Assay Reagents Others
    Poly(tetrafluoroethylene) (Fluorinated polymer; Fluoropolymer; PTFE) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Poly(tetrafluoroethylene)
  • HY-W002291
    p-Fluoro-L-phenylalanine

    4-Fluoro-L-phenylalanine

    		 Drug Derivative Infection
    p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a fluorinated derivative of L-phenylalanine (HY-N0215). p-Fluoro-L-phenylalanine specifically binds to the L-leucine-specific receptor of Escherichia coli, with a Kd value of 0.26 μM .
    p-Fluoro-L-phenylalanine
  • HY-32887
    3,5-Difluorophenylboronic acid

    		Biochemical Assay Reagents Drug Intermediate Others
    3,5-Difluorophenylboronic acid is a fluorinated arylboronic acid compound. As an important intermediate, 3,5-difluorophenylboronic acid can be used in the synthesis of other active compounds .
    3,5-Difluorophenylboronic acid
  • HY-W050049
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate

    		Biochemical Assay Reagents Others
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research .
    2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate
  • HY-W021482
    (4S)-1-Boc-4-fluoro-D-proline

    		Amino Acid Derivatives Drug Intermediate Others
    (4S)-1-Benzoylcarbonyl-4-fluorobutylproline ((2R,4R)-1-tert-butoxycarbonyl-4-fluoropyrrolidine-2-carboxylic acid) is a derivative of fluorinated proline and can be used as a pharmaceutical intermediate for the synthesis of various active compounds .
    (4S)-1-Boc-4-fluoro-D-proline
  • HY-B0139R
    Flucytosine (Standard)

    5-Fluorocytosine (Standard); NSC 103805 (Standard); Ro 2-9915 (Standard)

    		 Reference Standards Fungal Antibiotic Infection Cancer
    Flucytosine (Standard) is the analytical standard of Flucytosine. This product is intended for research and analytical applications. Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells .
    Flucytosine (Standard)
  • HY-W012911
    2,6-Difluoropyridine

    		Biochemical Assay Reagents Others
    2,6-Difluoropyridine is a fluorinated pyridine derivative. 2,6-Difluoropyridine adopts a planar conformation in its S0 electronic ground state and S1(π,π) excited state .
    2,6-Difluoropyridine
  • HY-124472
    2,4-Difluororesorcinol

    		Drug Intermediate Others
    2,4-Difluororesorcinol is a fluorinated building block .
    2,4-Difluororesorcinol
  • HY-115859
    SCH 25393

    		Bacterial Infection
    SCH 25393 is a potent antibacterial agent .
    SCH 25393
  • HY-P2496
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled

    		Endothelin Receptor Fluorescent Dye NF-κB COX Prostaglandin Receptor Apoptosis TNF Receptor Interleukin Related MMP Cardiovascular Disease Inflammation/Immunology Cancer
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled
  • HY-W010023
    2-Amino-3-bromo-5-fluoropyridine

    3-Bromo-5-fluoro-2-pyridinamine

    		 Drug Intermediate Others
    2-Amino-3-bromo-5-fluoropyridine (3-Bromo-5-fluoro-2-pyridinamine) is a drug intermediate that can be used for the synthesis fluorinated pyridines .
    2-Amino-3-bromo-5-fluoropyridine
  • HY-136595
    3,5-Difluoro-L-tyrosine

    		Phosphatase Others
    3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) .
    3,5-Difluoro-L-tyrosine
  • HY-15234R
    Fluticasone furoate (Standard)

    		Reference Standards Glucocorticoid Receptor Inflammation/Immunology
    Fluticasone furoate (Standard) is the analytical standard of Fluticasone furoate. This product is intended for research and analytical applications. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .
    Fluticasone furoate (Standard)
  • HY-W127832
    Ru(dpp)3(PF6)2
    1 Publications Verification

    		 Fluorescent Dye Others
    Ru(dpp)3(PF6)2 is a ruthenium (II) polypyridine complex and oxygen-sensing luminophore with excellent photostability and bright orange emission properties based on metal-to-ligand charge transfer (MLCT). Ru(dpp)3(PF6)2 undergoes oxygen-induced collisional luminescence quenching following the Stern-Volmer relationship, and can also engage in Förster-type resonance energy transfer with closed-form BTF6. Featuring excellent photophysical and electrochemical properties, Ru(dpp)3(PF6)2 is applied in studies on quenching-type oxygen sensors based on fluorinated ORMOSIL/xerogels and solid-state light-emitting devices .
    Ru(dpp)3(PF6)2
  • HY-172337
    Fluorexetamine hydrochloride

    3-Fluoro-2-oxo PCE hydrochloride; FXE hydrochloride

    		 Drug Derivative Neurological Disease
    Fluorexetamine (3-Fluoro-2-oxo PCE) hydrochloride is a fluorinated β-ketoarylcyclohexylamine .
    Fluorexetamine hydrochloride
  • HY-106218
    Flurocitabine

    5-Fluorocyclocytidine; 5'-Fluorocyclocytidine

    		 Nucleoside Antimetabolite/Analog Cancer
    Flurocitabine (5-Fluorocyclocytidine) is a fluorinated anlydride analog of cytosine arabinoside, partially hydrolysecl in vivo into two active antitumor substances (arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU)). Flurocitabine (5-Fluorocyclocytidine) has antitumor activity during phase I studies in acute leukemia and solid tumors .
    Flurocitabine
  • HY-W095635
    Tetramethylammonium fluoride tetrahydrate

    		Biochemical Assay Reagents Others
    Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.
    Tetramethylammonium fluoride tetrahydrate
  • HY-40156
    5-Fluoroindole

    		Bacterial Reactive Oxygen Species (ROS) Apoptosis Infection
    5-Fluoroindole is an orally active fluorinated indole derivative and antibacterial agent. 5-Fluoroindole induces ROS accumulation and triggers Apoptosis. 5-Fluoroindole inhibits the growth of pan-susceptible Mycobacterium tuberculosis (Mtb) H37Rv strains. 5-Fluoroindole has significant bactericidal activity against Pseudomonas syringae pv. actinidiae (Psa) with an EC50 of 15.34 μg/mL. 5-Fluoroindole introduces fluorine labeling for protein research. 5-Fluoroindole can be used in the study of tuberculosis and kiwifruit bacterial canker .
    5-Fluoroindole
  • HY-B0069R
    Fludarabine (Standard)

    F-ara-A (Standard); NSC 118218 (Standard)

    		 Reference Standards Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis Cancer
    Fludarabine (Standard) is the analytical standard of Fludarabine. This product is intended for research and analytical applications. Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
    Fludarabine (Standard)
  • HY-65254
    5-Amino-2-fluoropyridine

    		Biochemical Assay Reagents Drug Intermediate Others
    5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .
    5-Amino-2-fluoropyridine
  • HY-155869
    5-fluoro-dCTP

    5-Fluoro-2′-deoxycytidine 5′-triphosphate

    		 DNA/RNA Synthesis Others
    5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
    5-fluoro-dCTP
  • HY-W007614
    3-Fluoro-4-methoxybenzaldehyde

    3-Fluoro-para-anisaldehyde

    		 Drug Intermediate Cancer
    3-Fluoro-4-methoxybenzaldehyde (3-Fluoro-para-anisaldehyde) is a drug intermediate that can be used to synthesize the fluorinated derivative of Combretastatin A-4 (HY-N2146), which has anti-cancer activity.
    3-Fluoro-4-methoxybenzaldehyde
  • HY-139211
    Difluorinated Curcumin

    3,4-Difluorobenzylidene curcumin

    		 Reactive Oxygen Species (ROS) Cancer
    Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy .
    Difluorinated Curcumin
  • HY-105211
    KU-2285

    		Biochemical Assay Reagents Cancer
    KU-2285 is an orally active fluorinated 2-nitroimidazole hypoxic cell radiosensitizer. KU-2285 has higher lipophilicity, superior sensitizing activity to Etanidazole (HY-116972), and lower neurotoxicity. KU-2285 can be used in research related to tumor diagnosis .
    KU-2285
  • HY-W250129
    2,3,4,5-Tetrafluorobenzoyl chloride

    		Biochemical Assay Reagents Others
    2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.
    2,3,4,5-Tetrafluorobenzoyl chloride
  • HY-175149A
    (+)-2-Fluorodeoxyarbutin

    		Tyrosinase Others
    (+)-2-Fluorodeoxyarbutin is a fluorinated derivative of the tyrosinase inhibitor deoxyarbutin (HY-B1461).
    (+)-2-Fluorodeoxyarbutin
  • HY-32126R
    1-Fluoronaphthalene (Standard)

    		Adrenergic Receptor Serotonin Transporter Reference Standards Others
    1-Fluoronaphthalene (Standard) is the analytical standard of 1-Fluoronaphthalene. This product is intended for research and analytical applications. 1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene (Standard)
  • HY-134033A
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium

    2'-Fluoro dATP sodium

    		 Nucleoside Antimetabolite/Analog Infection
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium (2'-fluoro dATP) is a fluorinated derivative of ATP (HY-B2176). 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium is a substrate and an inhibitor for E.coli DNA-dependent RNA polymerase, with a Ki of 200 µM .
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium
  • HY-175377
    (-)-2-Fluorodeoxyarbutin

    		Tyrosinase Others
    (-)-2-Fluorodeoxyarbutin is a fluorinated derivative of the tyrosinase inhibitor deoxyarbutin .
    (-)-2-Fluorodeoxyarbutin
  • HY-79171
    3,4-Difluorophenylalanine

    		Biochemical Assay Reagents Others
    3,4-Difluorophenylalanine is a fluorinated peptide with gelation ability .
    3,4-Difluorophenylalanine
  • HY-155869A
    5-fluoro-dCTP sodium

    5-Fluoro-2′-deoxycytidine 5′-triphosphate sodium

    		 DNA/RNA Synthesis Others
    5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
    5-fluoro-dCTP sodium
  • HY-113719
    VM4-037

    		Carbonic Anhydrase Cancer
    VM4-037 can be used for the synthesis of VM4-037(18F). VM4-037(18F) is a fluorinated PET imaging agent for carbonic anhydrase IX .
    VM4-037
  • HY-162453
    Anticancer agent 204

    		Apoptosis MMP Cancer
    Anticancer agent 204 (Compound 6), a cinnamide fluorinated derivative, possesses anticancer activity. Anticancer agent 204 can arrest the cell cycle of HepG2 cells in the G1 phase and induce apoptosis by reducing the level of mitochondrial membrane polarization (MMP) .
    Anticancer agent 204
  • HY-121571
    Prallethrin

    		Insecticide Infection Cancer
    Prallethrin, a spatial mosquito repellent, is a non-fluorinated pyrethroid targeting lung surfactant proteins (SPs). prallethrin has vapor toxicity and can bind with the lung SPs by hydrogen and hydrophobic interactions, impairing functions of SPs. Prallethrin can be used for respiratory illness, pathogenic infections and malignancy research .
    Prallethrin
  • HY-B0983R
    Hydrocortisone 17-butyrate (Standard)

    Cortisol 17-butyrate (Standard); Hydrocortisone butyrate (Standard)

    		 Reference Standards Adrenergic Receptor Inflammation/Immunology Endocrinology
    Hydrocortisone 17-butyrate (Standard) is the analytical standard of Hydrocortisone 17-butyrate. This product is intended for research and analytical applications. Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid for use in psoriasis, eczema, and other inflammatory dermatoses. Hydrocortisone 17-butyrate inhibits granuloma formation in rats. Hydrocortisone 17-butyrate can induce vasoconstriction .
    Hydrocortisone 17-butyrate (Standard)
  • HY-B0248R
    Desonide (Standard)

    		Reference Standards Glucocorticoid Receptor Huntingtin Apoptosis Neurological Disease Inflammation/Immunology
    Desonide (Standard) is the analytical standard of Desonide. This product is intended for research and analytical applications. Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. Desonide can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis.
    Desonide (Standard)
  • HY-W422400
    Fluoroglutamine (2S,4R)

    		Biochemical Assay Reagents Others Cancer
    Fluoroglutamine (2S,4R) is a fluorinated derivative of glutamine. As a substrate for various aminotransferases, Fluoroglutamine (2S,4R) can be used as a tracer for positron emission tomography (PET) imaging. Fluoroglutamine (2S,4R) is applied in the research fields of tumor metabolism and imaging .
    Fluoroglutamine (2S,4R)

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