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  4. 1-Fluoronaphthalene

1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake.

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1-Fluoronaphthalene Chemical Structure

1-Fluoronaphthalene Chemical Structure

CAS No. : 321-38-0

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1-Fluoronaphthalene Related Antibodies

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Description

1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake[1].

In Vitro

1-Fluoronaphthalene (3 mg, 24 h) can be oxidized by C.elegans ATCC 36112 to form trans-3,4-dihydroxy-3,4-dihydro-1-fluoronaphthalene and trans-5,6-dihydroxy-5,6-dihydro-1-fluoronaphthalene and to form 1-fluoro-8-hydroxy-5-tetralone, 5-hydroxy-1-fluoronaphthalene and 4-hydroxy-1-fluoronaphthalene as well as glucosides, sulfates and glucuronide conjugates of these phenols[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Fluoronaphthalene Related Antibodies
Molecular Weight

146.16

Formula

C10H7F
CAS No.
Appearance

Liquid

Color

Colorless to yellow

SMILES

FC1=C(C=CC=C2)C2=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (684.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8418 mL 34.2091 mL 68.4182 mL
5 mM 1.3684 mL 6.8418 mL 13.6836 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.8418 mL 34.2091 mL 68.4182 mL 171.0454 mL
5 mM 1.3684 mL 6.8418 mL 13.6836 mL 34.2091 mL
10 mM 0.6842 mL 3.4209 mL 6.8418 mL 17.1045 mL
15 mM 0.4561 mL 2.2806 mL 4.5612 mL 11.4030 mL
20 mM 0.3421 mL 1.7105 mL 3.4209 mL 8.5523 mL
25 mM 0.2737 mL 1.3684 mL 2.7367 mL 6.8418 mL
30 mM 0.2281 mL 1.1403 mL 2.2806 mL 5.7015 mL
40 mM 0.1710 mL 0.8552 mL 1.7105 mL 4.2761 mL
50 mM 0.1368 mL 0.6842 mL 1.3684 mL 3.4209 mL
60 mM 0.1140 mL 0.5702 mL 1.1403 mL 2.8508 mL
80 mM 0.0855 mL 0.4276 mL 0.8552 mL 2.1381 mL
100 mM 0.0684 mL 0.3421 mL 0.6842 mL 1.7105 mL
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1-Fluoronaphthalene Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Fluoronaphthalene321-38-0Othersorganofluorinenaphthalene derivativesfluorinated aromaticsLY248686serotoninnoradrenaline uptakeInhibitorinhibitorinhibit

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