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Results for "

hPR

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Recombinant Proteins

2

Isotope-Labeled Compounds

9

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15373
    Fenretinide
    5+ Cited Publications

    4-hPR; ISLA-101

    		 RAR/RXR Autophagy Cancer
    Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.
    Fenretinide
  • HY-109583
    4-Oxofenretinide

    4-Oxo-4-hPR

    		 Apoptosis Reactive Oxygen Species (ROS) Drug Metabolite Cancer
    4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9 .
    4-Oxofenretinide
  • HY-W442049
    Hydroxypinacolone retinoate

    hPR

    		 RAR/RXR Inflammation/Immunology
    Hydroxypinacolone retinoate (HPR) is a retinol derivative, which binds directly with retinoic acid receptors (RARs). Hydroxypinacolone retinoate, when used in combination with Retinyl propionate, can be used in anti-skin aging research .
    Hydroxypinacolone retinoate
  • HY-RS06343
    HPR Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HPR Human Pre-designed siRNA Set A contains three designed siRNAs for HPR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HPR Human Pre-designed siRNA Set A
    HPR Human Pre-designed siRNA Set A
  • HY-15373R
    Fenretinide (Standard)

    4-hPR (Standard); ISLA-101 (Standard)

    		 Reference Standards RAR/RXR Autophagy Cancer
    Fenretinide (Standard) is the analytical standard of Fenretinide. This product is intended for research and analytical applications. Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.
    Fenretinide (Standard)
  • HY-109583S
    4-Oxofenretinide-d4

    4-Oxo-4-hPR-d4

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Drug Metabolite Apoptosis Cancer
    4-Oxofenretinide-d4 (4-Oxo-4-HPR-d4) is deuterium labeled 4-Oxofenretinide. 4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9 .
    4-Oxofenretinide-d4
  • HY-167638
    Fenretinide glucuronide

    4-hPR-O-glucuronide

    		 Drug Metabolite Cancer
    Fenretinide glucuronide (4-HPR-O-glucuronide) is a metabolite formed from Fenretinide (HY-15373) through glucuronidation. The formation of Fenretinide glucuronide enhances the water solubility of Fenretinide and facilitates its excretion. Fenretinide glucuronide holds potential for research in the field of cancer .
    Fenretinide glucuronide
  • HY-143957S
    Fenretinide glucuronide-d4

    4-hPR-O-glucuronide-d4

    		 Isotope-Labeled Compounds Others
    Fenretinide glucuronide-d4 is the deuterium labeled Fenretinide glucuronide .
    Fenretinide glucuronide-d4
  • HY-119080
    CP8754

    		Progesterone Receptor Endocrinology Cancer
    CP8754 is an orally active, selective human progesterone receptor (hPR) antagonist that blocks progesterone-mediated signaling pathways. CP8754 competitively inhibits the binding of [ 3H]-progesterone to hPR. And in vitro, CP8754 inhibits progesterone-dependent exogenous luciferase and endogenous alkaline phosphatase expression; while in vivo, CP8754 inhibits rabbit endometrial transformation. CP8754 does not significantly bind to human glucocorticoid receptors (hGR), estrogen receptors (hER), or rat androgen receptors (rAR). CP8754 can be used in the study of progesterone-related diseases such as breast cancer, endometriosis, uterine fibroids, and meningioma, as well as hormone-dependent tumors .
    CP8754

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