Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
human RBC
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "human RBC" in MCE Product Catalog:
11
Target:
Research Areas:
Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+-activated K + channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca 2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM .
2
2 Cited Publications
Cat. No.: HY-135416
CAS No.: 98072-47-0
Target:
1
1 Cited Publications
Target:
1
1 Cited Publications
Synonyms: BCX 34 dihydrochloride
Target:
Research Areas:
Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
Cat. No.: HY-P990068
CAS No.: 2643331-31-9
Synonyms: SRF617
Target:
Research Areas:
RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines .
Cat. No.: HY-168373
CAS No.: 99264-98-9
Target:
Research Areas:
1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PC is a phospholipid that can be found in human red blood cells (RBCs) .
Cat. No.: HY-106934
CAS No.: 133432-71-0
Synonyms: BCX 34
Target:
Research Areas:
Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines .
Cat. No.: HY-50694R
CAS No.: 289656-45-7
Synonyms: ICA-17043 (Standard)
Target:
Research Areas:
Senicapoc (Standard) is the analytical standard of Senicapoc. This product is intended for research and analytical applications. Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM .
Cat. No.: HY-P990843
Target:
Research Areas:
Cat. No.: HY-P990846
Target:
Research Areas:
Cat. No.: HY-106934AR
CAS No.: 2772702-10-8
Synonyms: BCX 34 dihydrochloride (Standard)
Research Areas:
Peldesine (dihydrochloride) (Standard) is the analytical standard of Peldesine (dihydrochloride). This product is intended for research and analytical applications. Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
Cat. No.: HY-180998
CAS No.: 1989688-84-7
Antibiofilm agent-18, a tetrahydropyrid derivative is a biofilm inhibitor. Antibiofilm agent-18 can disrupts S. aureus and P. aeruginosa biofilms and has low cytotoxicity. Antibiofilm agent-18 can be used for the research of bacterial infection .
Cat. No.: HY-P11821
Cat. No.: HY-183291
Target:
Bacterial DNA/RNA Synthesis DNA Alkylator/Crosslinker Reactive Oxygen Species (ROS) Penicillin-binding protein (PBP)
Research Areas:
Antibacterial agent 343 (Compound 47) is an Antibacterial agent. Antibacterial agent 343 binds to the allosteric site of PBP2a to open its active site. Antibacterial agent 343 disrupts bacterial cell membranes, leading to protein leakage. Antibacterial agent 343 interacts with DNA and inhibits replication and transcription. Antibacterial agent 343 induces ROS accumulation. Antibacterial agent 343 exhibits antibacterial activity against MRSA, Staphylococcus aureus, and Enterococcus faecalis. Antibacterial agent 343 can be used for the research of methicillin-resistant Staphylococcus aureus infections .
Cat. No.: HY-P991924
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
