139 Results for "

hydroxy fatty acid

" in MedChemExpress (MCE) Product Catalog:
Products (139)

139 Results for "hydroxy fatty acid" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-113679
CAS No.: 100403-19-8
Target:  

Telomerase

Research Areas:  

Metabolic Disease Endocrinology

Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .
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1
1 Cited Publications
Cat. No.: HY-W592871
CAS No.: 765-01-5
Synonyms: 10-HDA; Queen Bee acid
10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-α signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence .
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1
1 Cited Publications
Cat. No.: HY-N0468
CAS No.: 63279-13-0
Rebaudioside D is an orally active sweetener that targets and activates FXR, modulates Acetyl-CoA Carboxylase, and inhibits 3-hydroxy-3-methylglutaryl-CoA reductase. Rebaudioside D regulates bile acid homeostasis and lipid metabolism, reduces the synthesis rates of fatty acids and cholesterol, and exerts multiple effects including anti-adipogenesis, hepatoprotection, anti-steatosis, gut microbiota modulation, enhancement of secondary bile acid metabolism, anti-endotoxin activity, regulation of bile acid transport, and inhibition of bile acid efflux. Rebaudioside D also reduces body weight gain, visceral fat accumulation, hepatic triglyceride and cholesterol accumulation, hepatic lipid peroxidation, and decreases the circulating level of lipopolysaccharide-binding protein. Rebaudioside D additionally enhances the secondary bile acid metabolic pathway of intestinal bacteria, upregulates the gene expression of ileal organic solute transporter α, and downregulates the gene expression of hepatic bile salt export pump. Rebaudioside D does not affect glucose homeostasis, alter total caloric intake or fecal energy excretion, induce weight gain, exacerbate obesity, promote hepatic steatosis, impair brown adipose tissue function, nor change skeletal muscle metabolism-related proteins. Rebaudioside D can be used in diet-induced obesity and obesity-related research .
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Cat. No.: HY-W068212
CAS No.: 506-13-8
Synonyms: Juniperic acid
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma .
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Cat. No.: HY-W015874
CAS No.: 3739-30-8
2-Hydroxy-2-methylbutanoic acid is a branched-chain fatty acid. 2-Hydroxy-2-methylbutanoic acid accumulates at high levels in the culture supernatants of colorectal cancer-associated bacteria. 2-Hydroxy-2-methylbutanoic acid is also present in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease .
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Cat. No.: HY-142105
CAS No.: 3639-21-2
Purity:  ≥98.0%
Synonyms: 2-Ethyl-2-hydroxybutyric acid
2-Ethyl-2-hydroxybutanoic acid (2-Ethyl-2-hydroxybutyric acid) is a hydroxy fatty acid. 2-Ethyl-2-hydroxybutanoic is a metabolite of DEHP (HY-B1945) .
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Cat. No.: HY-165772
CAS No.: 34932-12-2
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

10-Hydroxy-12(Z)-octadecenoic acid is a hydroxy-unsaturated fatty acid that can be found in microorganisms such as lactic acid bacteria.
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Cat. No.: HY-W012017
CAS No.: 2507-55-3
Target:  

Enterovirus

Research Areas:  

Infection

2-Hydroxytetradecanoic acid is a 2-hydroxy long-chain fatty acid and a sphingolipid component. 2-Hydroxytetradecanoic acid inhibits cleavage between the enterovirus capsid proteins VP4 and VP2. 2-Hydroxytetradecanoic acid exhibits antiviral activity .
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Cat. No.: HY-N13284
CAS No.: 324575-43-1
Target:  

Fungal

13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .
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Cat. No.: HY-117586
CAS No.: 1636134-70-7
Purity:  ≥95.0%
9-PAHPA is a fatty acid esters of hydroxy fatty acid (FAHFA). FAHFAs are a new family of endogenous lipids, have antidiabetic and anti-inflammatory effects .
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Cat. No.: HY-116133
CAS No.: 17773-30-7
Purity:  98.25%
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

3-hydroxy Stearic acid is a long-chain saturated fatty acid and can be found in C. pyloridis .
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Cat. No.: HY-124355
CAS No.: 17427-21-3
Synonyms: 4-HHE
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

4-Hydroxy hexenal (4-HHE) is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA.
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Cat. No.: HY-116895
CAS No.: 1831135-30-8
Purity:  98.05%
Target:  

Androgen Receptor MAGL

Research Areas:  

Metabolic Disease

JJH260 is AIG1inhibitor, and inhibit the fluorophosphonate reactivity and fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1in HEK293T cells, with IC50 values of 0.50 μM and 0.57 μM, respectively .
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Cat. No.: HY-158583
CAS No.: 2126038-97-7
13-POHSA is one of fatty acid esters of hydroxy fatty acids (FAHFAs). 13-POHSA increases glucose-stimulated insulin secretion (GSIS) at a high glucose concentration .
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Cat. No.: HY-158584
CAS No.: 1997286-67-5
Synonyms: 9Z-Octadecenoic acid, 12-carboxy-1-pentyldodecyl ester
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

13-OAHSA is one of fatty acid esters of hydroxy fatty acids (FAHFAs). 13-OAHSA increases glucose-stimulated insulin secretion (GSIS) at a high glucose concentration .
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Cat. No.: HY-158650
CAS No.: 2005487-34-1
10-OAHSA is one of fatty acid esters of hydroxy fatty acids (FAHFAs). 10-POHSA increases glucose-stimulated insulin secretion (GSIS) at a high glucose concentration. 10-OAHSA reduces LPS (HY-D1056)-induced Tnf-α secretion in bone marrow-derived dendritic cells (BMDCs) .
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Cat. No.: HY-CE00556
CAS No.: 31429-10-4
Synonyms: 2-hydroxypalmitoyl-coenzyme A
Research Areas:  

Metabolic Disease

2-Hydroxypalmitoyl-CoA (2-Hydroxypalmitoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.
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Cat. No.: HY-131668
CAS No.: 1481636-43-4
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

9-POHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 9-POHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression .
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Cat. No.: HY-125143
CAS No.: 1831135-56-8
Purity:  99.90%
Target:  

MAGL

Research Areas:  

Metabolic Disease

ABC34 is an inactive control compound of JJH260. ABC34 does not inhibit the fluorophosphonate reactivity or fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1. ABC34 can inhibit both ABHD6 and PPT122 .
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Cat. No.: HY-128603
CAS No.: 1383119-39-8
Research Areas:  

Metabolic Disease

2-Hydroxyisobutyryl-CoA is a hydroxy fatty acyl-CoA. 2-Hydroxyisobutyryl-CoA mutase forms the isomer (S)-3-hydroxybutyryl-CoA .
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