2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 2-Hydroxy-2-methylbutanoic acid

2-Hydroxy-2-methylbutanoic acid 

Cat. No.: HY-W015874 Purity: ≥97.0%
COA Handling Instructions

2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.

For research use only. We do not sell to patients.

2-Hydroxy-2-methylbutanoic acid Chemical Structure

2-Hydroxy-2-methylbutanoic acid Chemical Structure

CAS No. : 3739-30-8

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Solid
100 mg USD 50 In-stock
500 mg USD 140 In-stock
1 g   Get quote  
5 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

118.13

Appearance

Solid

Formula

C5H10O3
CAS No.
SMILES

CCC(C)(O)C(O)=O
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (846.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.4653 mL 42.3263 mL 84.6525 mL
5 mM 1.6931 mL 8.4653 mL 16.9305 mL
10 mM 0.8465 mL 4.2326 mL 8.4653 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (21.16 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (21.16 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (21.16 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥97.0%

COA (248 KB) HNMR (184 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

2-Hydroxy-2-methylbutanoic acid3739-30-8Endogenous MetaboliteInhibitorinhibitorinhibit

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