9-PAHPA
Based on 1 Customer Validation
9-PAHPA is a fatty acid esters of hydroxy fatty acid (FAHFA). FAHFAs are a new family of endogenous lipids, have antidiabetic and anti-inflammatory effects.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 95.0%
- CAS No.: 1636134-70-7
- Formule: C32H62O4
- Masse moléculaire:510.83
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Stockage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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HY-116193
5-PAHSAAnti-Inflammatory Agent -
HY-158584
13-OAHSAFAHFA -
HY-W709961
5-OAHSAEndogenous Metabolite -
HY-131668
9-POHSAAnti-Inflammatory Agent -
HY-138177
Butyryl-Coenzyme A sodiumIntermediate Metabolite -
HY-113878
12-OAHSAAnti-Obese Agent -
HY-158583
13-POHSAFAHFA -
HY-131934
9-OAHSAAnti-Inflammatory reagent -
HY-130434
12-SAHSAFAHFA -
HY-116193R
5-PAHSA (Standard)Anti-Inflammatory Agent -
HY-130352
9-SAHSAFAHFA -
HY-133851
10-PAHSAFatty Ester
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Activité biologique
Description
IC50 & Target
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Human Endogenous Metabolite |
Chemical Information
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CAS No. 1636134-70-7
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Appearance Liquid
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Masse moléculaire 510.83
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Formule C32H62O4
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Color Colorless to light yellow
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SMILES
OC(CCCCCCCC(CCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Solution, -20°C, 2 years
Protocole
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Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
Pureté et documentation
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Fiche technique (263 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
9-PAHPA Related Classifications
HY-117586 Related Classifications
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