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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
indole ring
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "indole ring" in MCE Product Catalog:
Synonyms: Multhiomycin; RP 9671
Category:
Infection Microorganisms Antibiotics Animal Husbandry Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Cat. No.: HY-W048688
CAS No.: 1334509-86-2
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Fmoc-Trp(Me)-OH is an amino acid derivative. Fmoc-Trp(Me)-OH is formed by introducing a methyl group onto the nitrogen atom (N-1 position) of the indole ring of tryptophan (Trp) and protecting the amino group with Fmoc (9-fluorenylmethyloxycarbonyl). Fmoc-Trp(Me)-OH can be used in the synthesis of proteins or peptides .
Cat. No.: HY-W012848
CAS No.: 618-36-0
Synonyms: DL-α-Methylbenzylamine
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1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413) .
Cat. No.: HY-N10117
CAS No.: 138250-72-3
Category:
Alkaloids Hordeum vulgare var. coeleste Linnaeus Gramineae Other Diseases Plants Disease Research Fields Indole Alkaloids
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Cat. No.: HY-107486R
CAS No.: 56377-79-8
Synonyms: Multhiomycin (Standard); RP 9671 (Standard)
Category:
Microorganisms Antibiotics Animal Husbandry Disease Research Antibacterial Other Antibiotics
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Cat. No.: HY-30156
CAS No.: 10592-27-5
Synonyms: 7-Azaindoline
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2,3-Dihydro-7-azaindole (7-Azaindoline) is a cyclic secondary amine substrate with a fused aromatic ring, which serves as a substrate for hydrogenation reactions. 2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of lipase from Pseudomonas stutzeri. 2,3-Dihydro-7-azaindole is often used as an intermediate in organic synthesis, for example, in the preparation of indole compounds .
Cat. No.: HY-W007509
CAS No.: 5192-03-0
Synonyms: 5-Aminoindole
Cat. No.: HY-115004
CAS No.: 1006604-91-6
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MM-433593 is a potent and selective inhibitor of fatty acid amide hydrolase-1 (FAAH-1) that is orally administered to inhibit pain, inflammation, and related disorders. Pharmacokinetic studies of MM-433593 in macaques revealed a biphasic elimination profile with a rapid distribution phase and a slower elimination phase, with a systemic clearance of 8-11 mL/min/kg. MM-433593 exhibits moderate oral bioavailability (14-21%) and its metabolism primarily involves oxidation of the methyl group on the indole ring, resulting in a variety of sulfate, glucuronide, or glutathione-conjugated metabolites .
Cat. No.: HY-N19716
CAS No.: 34427-31-1
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Cat. No.: HY-186139
CAS No.: 2133853-85-5
Synonyms: TrpdU CEP
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Trp-dU Phosphoramidite (TrpdU CEP) is a phosphoramidite monomer modified with a tryptophan moiety (Trp, indole ring) attached via a linker to the C5 position of 2'-deoxyuridine (dU), used for solid-phase oligonucleotide synthesis.
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Cat. No.: HY-W115741S
CAS No.: 474267-40-8
Synonyms: (±)-1-Phenylethylamine-d3; DL-alpha-Methylbenzylamine-d3
Cat. No.: HY-D3120
CAS No.: 2246946-53-0
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LysoAIE2 is a Fluorescent probe for lysosomal viscosity detection and live-cell imaging. Its detection mechanism relies on the aggregation-induced emission effect: it exhibits only weak fluorescence in non-viscous media; in viscous environments, restricted intramolecular motion inhibits non-radiative energy dissipation pathways, thereby significantly enhancing fluorescence intensity. It achieves specific targeting of lysosomes through the proton acceptor property of its indole ring structure, while its hydroxyl group endows it with excellent water solubility. This probe is basically unaffected by microenvironmental polarity and pH within the range of pH 4.0 to pH 8.0, which avoids interference from these factors in viscosity measurement. LysoAIE2 has an emission wavelength of 570 nm. It can be used to monitor lysosomal viscosity changes during processes such as Dexamethasone (HY-14648)-induced lysosomal migration and starvation-induced mitophagy in live cells; at concentrations up to 40 μM, cell viability remains above 80%, demonstrating excellent biocompatibility .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
