720-00-3
720-00-3
Chemical Structure
(rac)-5-Hydroxykynurenine
- CAS No.: 720-00-3
- Formula:C10H12N2O4
- Molecular Weight:224.21
InChIKey: OTDQYOVYQQZAJL-UHFFFAOYSA-N
SMILES: O=C(C(CC(C1=CC(O)=CC=C1N)=O)N)O
Biological Activity: (rac)-5-Hydroxykynurenine is a urinary metabolite. (rac)-5-Hydroxykynurenine is generated via indole ring oxidative cleavage of 5-hydroxytryptophan (HY-N0122) catalyzed by indoleamine 2,3-dioxygenase[1][2].
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(rac)-5-Hydroxykynurenine | (rac)-5-Hydroxykynurenine is a urinary metabolite. (rac)-5-Hydroxykynurenine is generated via indole ring oxidative cleavage of 5-hydroxytryptophan (HY-N0122) catalyzed by indoleamine 2,3-dioxygenase. | |||||||||||||||||||||
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References
- [1]. Fujikawa M, et al. Role of Kynurenine and Its Derivatives in the Neuroimmune System. Int J Mol Sci. 2024;25(13):7144. Published 2024 Jun 28. [Content Brief]
- [2]. Fujiwara M, et al. Formation of 5-hydroxykynurenine and 5-hydroxykynurenamine from 5-hydroxytryptophan in rabbit small intestine. Proc Natl Acad Sci U S A. 1979;76(3):1145-1149. [Content Brief]
Keywords
