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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
68 Results for "
ketoacids
" in MedChemExpress (MCE) Product Catalog:
Products (68)
68 Results for "ketoacids" in MCE Product Catalog:
42
42 Publications Verification
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Neurological Disease Metabolic Disease Inflammation/Immunology
42
42 Publications Verification
Cat. No.: HY-P0014B
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9
9 Cited Publications
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BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) . BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM .
3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3
3 Cited Publications
Cat. No.: HY-P3462A
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1
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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1
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1
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1
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1
1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
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1
1 Cited Publications
Cat. No.: HY-P10218A
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1
1 Cited Publications
Cat. No.: HY-P10869
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Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
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Cat. No.: HY-159648
CAS No.: 2936625-34-0
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PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats .
Cat. No.: HY-P11285A
Synonyms: Long acting GIPRA-1 TFA
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Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
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Cat. No.: HY-173527
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PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders .
Cat. No.: HY-155157
Purity: 98.66%
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Cat. No.: HY-P0014S1
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Cat. No.: HY-P10271
Synonyms: NNC0090-2746; MAR709; RO6811135
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
