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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
lapatinib
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "lapatinib" in MCE Product Catalog:
95
Target:
Research Areas:
Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
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95 Publications Verification
Cat. No.: HY-50898A
CAS No.: 388082-77-7
Synonyms: GW572016 ditosylate; GW2016 ditosylate
Target:
Research Areas:
Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
95
95 Publications Verification
Cat. No.: HY-50898B
CAS No.: 388082-78-8
Synonyms: GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate
Target:
Research Areas:
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
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1 Cited Publications
Selatinib is an orally active EGFR and HER2 tyrosine kinase inhibitor with IC50 values of 13.0 nM and 8.5 nM, respectively. Selatinib undergoes oxidative metabolism in vivo to produce Lapatinib (HY-50898). Selatinib inhibits the growth of breast, gastric and ovarian tumors. Selatinib can be used in research related to gastric cancer, breast cancer and ovarian cancer .
Cat. No.: HY-50898S4
CAS No.: 1009307-23-6
Synonyms: GW572016-d7; GW2016-d7
Cat. No.: HY-P3498
CAS No.: 914009-84-0
Synonyms: ZP1846
Cat. No.: HY-172970
CAS No.: 3093763-71-1
Target:
Research Areas:
HQY1428 is an orally active CDK12 inhibitor. HQY1428 inhibits DNA replication, causes G2/M arrest in SKOV3 cells, induces DNA double-strand breaks and apoptosis. HQY1428 has anti-tumor activity in the SKOV3 xenograft mouse model. HQY1428 combined with the HER2 inhibitor Lapatinib (HY-50898) in the NCI-N87 xenograft mouse model produces a synergistic therapeutic effect .
Cat. No.: HY-50898S1
Synonyms: GW572016-d7 dihydrochloride; GW2016-d7 dihydrochloride
Cat. No.: HY-50898S
CAS No.: 1184263-99-7
Synonyms: GW572016-d4; GW2016-d4
Cat. No.: HY-P11197
CAS No.: 895547-36-1
Target:
Research Areas:
Cat. No.: HY-174414
EGFR/HER2-IN-18 is a stable EGFR/HER2 dual inhibitor with IC50 values of 0.09 (EGFR) and 0.08 μM (HER2) respectively. EGFR/HER2-IN-18 exhibits broad-spectrum anti-cancer activity. EGFR/HER2-IN-18 induces MCF-7 cells apoptosis and inhibits the cell cycle. EGFR/HER2-IN-18 can be used for the study of breast cancer .
Cat. No.: HY-50898R
CAS No.: 231277-92-2
Synonyms: GW572016 (Standard); GW2016 (Standard)
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Research Areas:
Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-W777297
CAS No.: 1246819-08-8
Cat. No.: HY-50898AR
CAS No.: 388082-77-7
Synonyms: GW572016 ditosylate (Standard); GW2016 ditosylate (Standard)
Target:
Research Areas:
Lapatinib (ditosylate) (Standard) is the analytical standard of Lapatinib (ditosylate). This product is intended for research and analytical applications. Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898BR
CAS No.: 388082-78-8
Synonyms: GW572016 ditosylate monohydrate (Standard); GW2016 ditosylate monohydrate (Standard)
Target:
Research Areas:
Lapatinib (ditosylate monohydrate) (Standard) is the analytical standard of Lapatinib (ditosylate monohydrate). This product is intended for research and analytical applications. Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898CS
CAS No.: 2749856-05-9
Synonyms: GW572016-d4 tosylate; GW2016-d4 tosylate
Cat. No.: HY-50898S2
CAS No.: 2748212-14-6
Synonyms: GW572016-d5; GW2016-d5
Cat. No.: HY-50898C
CAS No.: 1187538-35-7
Synonyms: GW572016 tosylate; GW2016 tosylate
Target:
Research Areas:
Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898S3
CAS No.: 1184264-15-0
Synonyms: GW572016-d4-1; GW2016-d4-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
