1246819-08-8
1246819-08-8
Chemical Structure
Lapatinib-13C215N
- CAS No.: 1246819-08-8
- Formula:C3413C2H34ClFN315NO7S2
- Molecular Weight:756.24
InChIKey: OZDXXJABMOYNGY-OSUMFKEWSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(O)=O.FC2=CC(COC3=CC=C(NC4=NC=NC5=CC=C(C=C54)C6=CC=C(O6)C[15NH][13CH2][13CH2]S(C)(=O)=O)C=C3Cl)=CC=C2
Biological Activity: Lapatinib-13C2,15N Ditosylate is the 13C- and 15N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
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Lapatinib-13C215N | Lapatinib-13C2,15N Ditosylate is the 13C- and 15N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively. | |||||||||||||||||||||
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Lapatinib ditosylate (Standard) | ≥98% | Lapatinib (ditosylate) (Standard) is the analytical standard of Lapatinib (ditosylate). This product is intended for research and analytical applications. Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively. | ||||||||||||||||||||
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Lapatinib ditosylate | 99.98% | Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively. | ||||||||||||||||||||
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References
