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lepidopteran

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (1) Apoptosis (1) Caspase (1) Environmental Pollutants (2) Insecticide (7) nAChR (1) NOD-like Receptor (NLR) (1) Parasite (2) Reference Standards (1)
By Research Areas:	Infection (4) Inflammation/Immunology (1) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145298

Dicloromezotiaz	nAChR	Infection
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera .

HY-N7400

Phaseoloidin	NOD-like Receptor (NLR) Caspase Insecticide	Inflammation/Immunology
Phaseoloidin is an orally active multi-target inhibitor. Phaseoloidin inhibits the activation of the NLRP3 inflammasome and blocks the caspase-11-GSDMD pyroptosis axis. Phaseoloidin reduces the expression of collagen-degrading enzymes to maintain the integrity of cartilage matrix. Phaseoloidin activates the AMPK/mTOR pathway to enhance autophagic function. Phaseoloidin exerts adverse effects on the growth and development of Manduca sexta and Spodoptera littoralis larvae, inhibits larval growth, and thereby helps Nicotiana attenuata defend against lepidopteran herbivorous insects. Phaseoloidin is applicable to research related to acute gouty arthritis and pulmonary fibrosis .

HY-133204

Chlorfluazuron IKI-7899	Environmental Pollutants Insecticide	Others
Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests .

HY-W098556

4-Hydroxyhygric acid	Insecticide	Infection
4-Hydroxyhygric acid is a compound isolated from leaves of five species of the leguminous tropical tree Copuiferq. 4-Hydroxyhygric acid is the inhibitor of larval development of the seed-feeding bruchid beetle Callosobruchus maculatus and to have significant feeding deterrence of the leaf-feeding lepidopteran Spodoprera littoralis .

HY-133204R

Chlorfluazuron (Standard) IKI-7899 (Standard)	Insecticide Reference Standards	Others
Chlorfluazuron (Standard) is the analytical standard of Chlorfluazuron. This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests .

HY-169999

AAP4	Parasite	Infection
AAP4 is a potent OfChi-h and OfHex1 inhibitor with K_i values of 29.3 nM and 4.9 μM, respectively. AAP4 shows insecticidal activity for lepidopteran pests Ostrinia furnacalis .

HY-149697

Insecticidal agent 6	Parasite	Others
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC₅₀ value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .

HY-149864

Insecticidal agent 3	Insecticide	Others
Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs)，with K_is of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .

HY-W108418

(Z)-8-Dodecen-1-ol cis-8-Dodecen-1-ol	Environmental Pollutants	Others
(Z)-8-Dodecen-1-ol (cis-8-Dodecen-1-ol) is an active straight chain lepidopteran pheromone (SCLP) .

HY-N10681

Evonimine Euonine	Others	Others
Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis .

HY-N15634

Anticopalic acid	Insecticide	Neurological Disease
Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests .

HY-B2052A

Thiosultap monosodium Monosultap	Insecticide Angiotensin-converting Enzyme (ACE) Apoptosis	Infection
Thiosultap monosodium (Monosultap) is a broad-spectrum insecticide and a competitive inhibitor of acetylcholine. Thiosultap monosodium exerts contact and stomach poisoning effects through systemic conduction in field pests. Thiosultap monosodium has teratogenic effects, induces notochord malformations in zebrafish embryos, and causes apoptosis and abnormally elevated cell proliferation in partial notochord tissues of zebrafish. Thiosultap monosodium is applicable to the research of controlling rice stem borers .

Phaseoloidin	Structural Classification Monophenols other families Classification of Application Fields Other Diseases Phenols Plants Disease Research Fields Source Classification	NOD-like Receptor (NLR) Caspase Insecticide
Phaseoloidin is an orally active multi-target inhibitor. Phaseoloidin inhibits the activation of the NLRP3 inflammasome and blocks the caspase-11-GSDMD pyroptosis axis. Phaseoloidin reduces the expression of collagen-degrading enzymes to maintain the integrity of cartilage matrix. Phaseoloidin activates the AMPK/mTOR pathway to enhance autophagic function. Phaseoloidin exerts adverse effects on the growth and development of Manduca sexta and Spodoptera littoralis larvae, inhibits larval growth, and thereby helps Nicotiana attenuata defend against lepidopteran herbivorous insects. Phaseoloidin is applicable to research related to acute gouty arthritis and pulmonary fibrosis .

4-Hydroxyhygric acid	Infection Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Plants Disease Research Fields Source Classification	Insecticide
4-Hydroxyhygric acid is a compound isolated from leaves of five species of the leguminous tropical tree Copuiferq. 4-Hydroxyhygric acid is the inhibitor of larval development of the seed-feeding bruchid beetle Callosobruchus maculatus and to have significant feeding deterrence of the leaf-feeding lepidopteran Spodoprera littoralis .

(Z)-8-Dodecen-1-ol cis-8-Dodecen-1-ol	Structural Classification Natural Products Animals Source Classification	Environmental Pollutants
(Z)-8-Dodecen-1-ol (cis-8-Dodecen-1-ol) is an active straight chain lepidopteran pheromone (SCLP) .

Evonimine Euonine	Sesquiterpenes Celastraceae Pyridine Alkaloids Tripterygium wilfordii Hook. f. Plants Source Classification	Others
Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis .

Anticopalic acid	Structural Classification Ketones, Aldehydes, Acids Labiatae Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb. Plants Source Classification	Insecticide
Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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lepidopteran

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