545 Results for "

mPEG

" in MedChemExpress (MCE) Product Catalog:
Products (545)

545 Results for "mPEG" in MCE Product Catalog:

26
26 Publications Verification
Cat. No.: HY-112764
CAS No.: 160743-62-4
Purity:  98.40%
mPEG2000-DMG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. mPEG2000-DMG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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1 Cited Publications
Cat. No.: HY-124011
CAS No.: 356066-46-1
Purity:  ≥95.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG3-aldehyde is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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1 Cited Publications
Cat. No.: HY-120237
CAS No.: 170572-38-0
Purity:  ≥97.0%
Research Areas:  

Cancer

m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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1 Cited Publications
Cat. No.: HY-130408
CAS No.: 184357-46-8
Purity:  ≥97.0%
Research Areas:  

Cancer

m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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1 Cited Publications
Cat. No.: HY-W018174
CAS No.: 74654-07-2
Research Areas:  

Cancer

m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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1 Cited Publications
Cat. No.: HY-W040214
CAS No.: 85030-56-4
Research Areas:  

Cancer

m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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1 Cited Publications
Cat. No.: HY-138424
CAS No.: 2745717-94-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG15-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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1 Cited Publications
Cat. No.: HY-W040236
CAS No.: 869718-81-0
Research Areas:  

Cancer

m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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1 Cited Publications
Cat. No.: HY-124011A
CAS No.: 356066-46-1
Purity:  98.00%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG3-aldehyde (stabilized with BHT) is a PROTAC linker that belongs to the PEG class and can be used in the synthesis of PROTACs .
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1 Cited Publications
Cat. No.: HY-142978
CAS No.: 156543-00-9
Synonyms: DSPE-mPEG2000
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery .
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1 Cited Publications
Cat. No.: HY-144013
CAS No.: 474922-77-5
Synonyms: DSPE-mPEG2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
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1 Cited Publications
Cat. No.: HY-112760
CAS No.: 247925-28-6
Purity:  ≥98.0%
Synonyms: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
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1 Cited Publications
Cat. No.: HY-140319
Purity:  98.41%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-mPEG (MW 5kDa) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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1 Cited Publications
Cat. No.: HY-D1567
CAS No.: 2708152-94-5
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
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Cat. No.: HY-W020780
CAS No.: 724722-89-8
Synonyms: mPEG5000-Maleimide
mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .
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Cat. No.: HY-140698
CAS No.: 92451-01-9
Purity:  ≥95.0%
Synonyms: mPEG5000-SC; mPEG5000-Succinimidyl ester
m-PEG5000-NHS ester (mPEG5000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
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Cat. No.: HY-140679
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG20000-NH2
mPEG20000-amine (mPEG20000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG20000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140676
CAS No.: 80506-64-5
Purity:  99.57%
Synonyms: mPEG2000-NH2
mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140677
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG5000-NH2
mPEG5000-amine (mPEG5000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG5000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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