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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
mRNA transfection efficiency
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "mRNA transfection efficiency" in MCE Product Catalog:
50
50 Cited Publications
Synonyms: C14-494
Cat. No.: HY-170704
CAS No.: 1480940-53-1
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DSPE-PEG2000-TCO is a click chemistry coupling partner. DSPE-PEG2000-TCO undergoes a reverse electron-demand Diels-Alder click reaction to form a covalent linkage with tetrazine-modified Cetuximab (HY-P9905). DSPE-PEG2000-TCO maintains the stability of lipid nanoparticles (LNPs) and has high mRNA encapsulation efficiency, which supports cellular uptake and mRNA transfection. DSPE-PEG2000-TCO is used to prepare EGFR-targeted and APN-targeted mRNA-loaded LNPs, mediating receptor-dependent endocytosis, mRNA delivery, and intestinal epithelial transcytosis .
Cat. No.: HY-134541GL
CAS No.: 2089251-47-6
Cat. No.: HY-134541S6
Cat. No.: HY-134541G
CAS No.: 2089251-47-6
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
Cat. No.: HY-171898
CAS No.: 3046404-81-0
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Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23). Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines .
Cat. No.: HY-150358
Synonyms: Beta-galactosidase mRNA
β-galactosidase mRNA encodes β-galactosidase, a protein product of the bacterial LacZ gene. β-galactosidase catalyzes the conversion of β-galactosides into monosaccharides which could be used as a common marker to assess transfection efficiency.
Cat. No.: HY-177921
CAS No.: 3058580-71-2
PL53 is a kind of cycloalkylamine lipid nanoparticles. PL53 exhibits outstanding transfection efficiency both in vitro and in vivo, especially showing strong protein expression ability and potential tissue targeting after intramuscular injection. PL53 can be used for the study of nucleic acid delivery .
Cat. No.: HY-174501
Synonyms: Beta-galactosidase mRNA (5moU)
β-galactosidase mRNA (5moU) encodes β-galactosidase, a protein product of the bacterial LacZ gene. β-galactosidase catalyzes the conversion of β-galactosides into monosaccharides which could be used as a common marker to assess transfection efficiency. The incorporation of 5moU can reduce the immunogenicity of the resulting mRNA.
Cat. No.: HY-171897
CAS No.: 3031773-77-7
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E10i-494 is an ionizable cationic branched endosomal disruptor (BEND) lipid. E10i-494 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vitro. E10i-494 can enhance transfection efficiency .
Cat. No.: HY-159870
CAS No.: 2778182-26-4
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E12CA1A3 is a lipid transfection reagent that boosts the delivery efficiency of mRNA .
Cat. No.: HY-184363
CAS No.: 2153563-36-9
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C14-306 is an ionizable lipid with a linear 306 amine core and a C14 alkyl tail. C14-306 enhances brain transfection efficiency. Lipid nanoparticles (LNP) formulated with C14-306 promote mRNA delivery, increase neuronal transfection rate, and facilitate Cre-mediated recombination in the brain, while reducing off-target expression in the liver .
Cat. No.: HY-150359
Synonyms: Beta-galactosidase mRNA (N1-Methylpseudo-UTP)
β-galactosidase mRNA (N1-Methylpseudo-UTP) encodes β-galactosidase, a protein product of the bacterial LacZ gene. β-galactosidase catalyzes the conversion of β-galactosides into monosaccharides which could be used as a common marker to assess transfection efficiency. The incorporation of N1-Methyl-pseudo-UTP can reduce the immunogenicity of the resulting mRNA.
Cat. No.: HY-P12013
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Cat. No.: HY-185679
CAS No.: 2991244-19-8
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W19-LNP is a lipid nanoparticle formulated with a Ugi-reaction-derived ionizable lipid (W19). W19-LNP demonstrates highly selective mRNA delivery to the spleen in female BALB/c mice upon intravenous administration. W19-LNP can be used for the research of mRNA-based vaccine delivery, immune cell reprogramming, and gene-engineered cell preparation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
