12 Results for "

modified nucleobases

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "modified nucleobases" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-112582C
CAS No.: 3056945-59-3
Purity:  99.70%
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
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1
1 Cited Publications
Cat. No.: HY-112582A
CAS No.: 1428903-59-6
Synonyms: 1-Methylpseudouridine-5′-triphosphate
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
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Cat. No.: HY-115642
CAS No.: 86694-45-3
Purity:  98.88%
Research Areas:  

Metabolic Disease

preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity .
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Cat. No.: HY-130802
CAS No.: 2149-76-0
Purity:  99.31%
Target:  

Fungal Influenza Virus

Research Areas:  

Infection Cancer

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses .
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Cat. No.: HY-117813
CAS No.: 20235-78-3
Purity:  99.73%
2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV) .
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Cat. No.: HY-112582B
Synonyms: 1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) tetralithium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability .
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Cat. No.: HY-126060
CAS No.: 879-08-3
Purity:  99.84%
Research Areas:  

Cancer

9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .
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Cat. No.: HY-112582AGL
CAS No.: 1428903-59-6
Synonyms: 1-Methylpseudouridine-5′-triphosphate (GMP like)
N1-Methylpseudouridine-5′-triphosphate (GMP like) (1-Methylpseudouridine-5′-triphosphate (GMP like)) is N1-Methylpseudouridine-5′-triphosphate (HY-112582A) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
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Cat. No.: HY-P11690
CAS No.: 791778-61-5
Research Areas:  

Cancer

Fmoc-Aeg-OBn is a benzyl-protected N-(2-aminoethyl)-glycine PNA backbone derivative. Fmoc-Aeg-OBn serves as a key intermediate for the synthesis of Fmoc-protected PNA monomers with modified nucleobases. Fmoc-Aeg-OBn can be used to prepare PNA with unique physicochemical properties, which is suitable for antisense and gene diagnostic applications. Fmoc-Aeg-OBn is applicable to cancer-related research .
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Cat. No.: HY-W574398
CAS No.: 172405-45-7
Research Areas:  

Others

Fmoc-Aeg-OH is a peptide nucleic acid (PNA) backbone intermediate and an Fmoc-protected carboxylic acid. Fmoc-Aeg-OH can be coupled with base acetic acids to synthesize Fmoc-protected PNA monomers, including those with modified bases .
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Cat. No.: HY-P11685
CAS No.: 2245800-85-3
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Fmoc-PNA-thioU(PMB)-OH features a thiouracil base protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone, designed for incorporating modified PNA bases into oligonucleotides to study binding properties.
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Cat. No.: HY-403689
CAS No.: 1095275-70-9
Research Areas:  

Others

Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .
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