879-08-3
879-08-3
Chemical Structure
9-Ethylguanine
- CAS No.: 879-08-3
- Formula:C7H9N5O
- Molecular Weight:179.18
IUPAC Name: 2-amino-9-ethyl-1,9-dihydro-6H-purin-6-one
InChIKey: WDOYBEPLTCFIRQ-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=C(N1)N)N(C=N2)CC
Biological Activity: 9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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9-Ethylguanine | 99.84% | 9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety. | ||||||||||||||||||||
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References
- [1]. Uemura M, et al. An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic profiles. Metallomics. 2012;4(7):686-692. [Content Brief]
- [2]. Hanif M, et al. Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. Front Chem. 2013;1:27. Published 2013 Oct 31. [Content Brief]
