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  4. preQ1 dihydrochloride

preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity.

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preQ1 dihydrochloride Chemical Structure

preQ1 dihydrochloride Chemical Structure

CAS No. : 86694-45-3

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5 mg USD 110 In-stock
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Based on 1 publication(s) in Google Scholar

preQ1 dihydrochloride Related Antibodies

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Description

preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].

Molecular Weight

252.10

Formula

C7H11Cl2N5O
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C1C2=C(NC=C2CN)N=C(N)N1.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (495.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9667 mL 19.8334 mL 39.6668 mL
5 mM 0.7933 mL 3.9667 mL 7.9334 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9667 mL 19.8334 mL 39.6668 mL 99.1670 mL
5 mM 0.7933 mL 3.9667 mL 7.9334 mL 19.8334 mL
10 mM 0.3967 mL 1.9833 mL 3.9667 mL 9.9167 mL
15 mM 0.2644 mL 1.3222 mL 2.6445 mL 6.6111 mL
20 mM 0.1983 mL 0.9917 mL 1.9833 mL 4.9583 mL
25 mM 0.1587 mL 0.7933 mL 1.5867 mL 3.9667 mL
30 mM 0.1322 mL 0.6611 mL 1.3222 mL 3.3056 mL
40 mM 0.0992 mL 0.4958 mL 0.9917 mL 2.4792 mL
50 mM 0.0793 mL 0.3967 mL 0.7933 mL 1.9833 mL
60 mM 0.0661 mL 0.3306 mL 0.6611 mL 1.6528 mL
80 mM 0.0496 mL 0.2479 mL 0.4958 mL 1.2396 mL
100 mM 0.0397 mL 0.1983 mL 0.3967 mL 0.9917 mL
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preQ1 dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

preQ186694-45-3preQ 1preQ-1OthersnucleobasequeuineprecursoraptamerPreQ1 riboswitchInhibitorinhibitorinhibit

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