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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
myofibril
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "myofibril" in MCE Product Catalog:
2
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Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model .
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Decamethonium Bromide is an acetylcholine receptor inhibitor and muscle relaxant. Decamethonium Bromide first induces depolarization of skeletal muscles, and then binds to postsynaptic acetylcholine receptors to induce persistent paralysis .\n
Cat. No.: HY-137749A
Synonyms: 2'-Deoxy-3'-MANT-ADP trisodium
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MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y12 receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils .
Cat. No.: HY-109121R
CAS No.: 1345410-31-2
Synonyms: CK-2127107 (Standard)
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Reldesemtiv (Standard) is the analytical standard of Reldesemtiv (HY-109121). This product is intended for research and analytical applications. Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model .
Cat. No.: HY-134248
CAS No.: 10058-66-9
Synonyms: 7-Deazaadenosine 5'-triphosphate
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Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) (Compound II) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate induces weak contraction of rabbit psoas myofibrils .
Cat. No.: HY-134248A
Synonyms: 7-Deazaadenosine 5'-triphosphate tetrasodium
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Tubercidin 5'-triphosphate tetrasodium (7-Deazaadenosine 5'-triphosphate tetrasodium) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate tetrasodium is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate tetrasodium induces weak contraction of rabbit psoas myofibrils .
Cat. No.: HY-184098
CAS No.: 2770252-94-1
Synonyms: Lomasemtivum
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Lomasemtiv (Lomasemtivum) is a Troponin activator. Lomasemtiv activates skeletal muscle myofibrils. Lomasemtiv is applicable to sarcopenia research .
Cat. No.: HY-17681
CAS No.: 2839464-02-5
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Myosin-IN-5 (example 3) is a selective cardiac myosin inhibitor with an IC50 of 1.5 μM. Myosin-IN-5 shows much less effective in inhibiting skeletal myofibril activity (IC50 of 43.4 μM). Myosin-IN-5 can be used for the study of hypertrophic cardiomyopathy (HCM) and cardiac diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
