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Cat. No.: HY-184098

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Lomasemtiv

(Synonyms: Lomasemtivum)

Lomasemtiv (Lomasemtivum) is a Troponin activator. Lomasemtiv activates skeletal muscle myofibrils. Lomasemtiv is applicable to sarcopenia research.

For research use only. We do not sell to patients.

CAS No.: 2770252-94-1
Formula: C₁₃H₁₇FN₄O₂
Molecular Weight:280.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lomasemtiv Chemical Structure

CAS No.: 2770252-94-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

Lomasemtiv (Lomasemtivum) is a Troponin activator. Lomasemtiv activates skeletal muscle myofibrils. Lomasemtiv is applicable to sarcopenia research^[1]^[2].

All Calcium Channel Isoforms :

In Vitro

Lomasemtiv (Compound 10) rapidly activates fibers in rabbit skeletal muscle myofibrils, with an AC1.4 of 0.71 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2770252-94-1
Molecular Weight 280.30
Formula C₁₃H₁₇FN₄O₂
SMILES

CC[C@@H]([C@]1([H])N(CC2=C(F)C=NC=C2NC1=O)C(N)=O)C
Synonyms

Lomasemtivum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. International Nonproprietary
Names for Pharmaceutical
Substances (INN). WHO Drug Information, Vol. 39, No. 4, 2025.

[2]. Bradley P, et al. Bicyclic 1,4-diazepanones and therapeutic uses thereof. WO2022099011A1. WIPO (PCT). 2021-11-05.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
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Purity & Documentation
References

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Lomasemtiv

All Calcium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Lomasemtiv Related Classifications

HY-184098 Related Classifications