2839464-02-5
2839464-02-5
Chemical Structure
Myosin-IN-5
- CAS No.: 2839464-02-5
- Formula:C16H18F2N4O3
- Molecular Weight:352.34
InChIKey: XDTGZAPJARZCOH-VIFPVBQESA-N
SMILES: O=C(N1C2CCOCC2)NC(N[C@H](C3=CC=C(F)C=C3F)C)=NC1=O
Biological Activity: Myosin-IN-5 (example 3) is a selective cardiac myosin inhibitor with an IC50 of 1.5 μM. Myosin-IN-5 shows much less effective in inhibiting skeletal myofibril activity (IC50 of 43.4 μM). Myosin-IN-5 can be used for the study of hypertrophic cardiomyopathy (HCM) and cardiac diseases[1].
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Myosin-IN-5 | Myosin-IN-5 (example 3) is a selective cardiac myosin inhibitor with an IC50 of 1.5 μM. Myosin-IN-5 shows much less effective in inhibiting skeletal myofibril activity (IC50 of 43.4 μM). Myosin-IN-5 can be used for the study of hypertrophic cardiomyopathy (HCM) and cardiac diseases. | |||||||||||||||||||||
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References
Keywords
