MANT-dADP trisodium
MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y12 receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils.
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- Formel: C18H19N6Na3O10P2
- Molecular Weight:610.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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Molecular Weight 610.29
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Formel C18H19N6Na3O10P2
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SMILES
NC(N=CN=C12)=C1N=CN2[C@@H]3O[C@H](COP(OP(O[Na])(O[Na])=O)(O[Na])=O)[C@@H](OC(C4=C(C=CC=C4)NC)=O)C3
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Synonyms
2'-Deoxy-3'-MANT-ADP trisodium
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Bujalowski W, et al., Structural characteristics of the nucleotide-binding site of Escherichia coli primary replicative helicase DnaB protein. Studies with ribose and base-modified fluorescent nucleotide analogs. Biochemistry. 1994 Apr 19;33(15):4682-94. [Content Brief]
[2]. Schmidt P, et al., Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12. Mol Pharmacol. 2013 Jan;83(1):256-66. [Content Brief]
[3]. Gunther LK, et al., Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils. Biochemistry. 2016 Mar 29;55(12):1887-97. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)