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Cat. No.: HY-137749A

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MANT-dADP trisodium

Name: MANT-dADP trisodium
Brand: MedChemExpress
SKU: HY-137749A
Availability: PreOrder

(Synonyms: 2'-Deoxy-3'-MANT-ADP trisodium)

MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y₁₂ receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils.

For research use only. We do not sell to patients.

Formula: C₁₈H₁₉N₆Na₃O₁₀P₂
Molecular Weight:610.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

MANT-dADP trisodium Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 610.29
Formula C₁₈H₁₉N₆Na₃O₁₀P₂
SMILES

NC(N=CN=C12)=C1N=CN2[C@@H]3O[C@H](COP(OP(O[Na])(O[Na])=O)(O[Na])=O)[C@@H](OC(C4=C(C=CC=C4)NC)=O)C3
Synonyms

2'-Deoxy-3'-MANT-ADP trisodium
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bujalowski W, et al., Structural characteristics of the nucleotide-binding site of Escherichia coli primary replicative helicase DnaB protein. Studies with ribose and base-modified fluorescent nucleotide analogs. Biochemistry. 1994 Apr 19;33(15):4682-94. [Content Brief]

[2]. Schmidt P, et al., Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12. Mol Pharmacol. 2013 Jan;83(1):256-66. [Content Brief]

[3]. Gunther LK, et al., Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils. Biochemistry. 2016 Mar 29;55(12):1887-97. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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