Search Result
Results for "
nitroimidazole
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
11
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0318
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-
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- HY-13801
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HOE 239
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Parasite
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Infection
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Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei .
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- HY-B0177
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-
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- HY-N0195
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2-nitroimidazole
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MOFs
Bacterial
Antibiotic
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Infection
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Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
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-
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- HY-B0508
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Ro 7-0207
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Bacterial
Parasite
Antibiotic
Hedgehog
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Infection
Cancer
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Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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-
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- HY-B1244
-
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1,2-Dimethyl-5-nitroimidazole
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Environmental Pollutants
Antibiotic
Bacterial
Parasite
|
Infection
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Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections .
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-
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- HY-W008216
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Hydroxy Dimetridazole
|
Drug Metabolite
Parasite
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Infection
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HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
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- HY-U00118
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- HY-16349
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K-1900
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Parasite
Antibiotic
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Infection
Cancer
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Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
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- HY-15781
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Bacterial
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Infection
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Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
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- HY-B0318R
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-
-
- HY-136436
-
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Drug Metabolite
Antibiotic
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
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Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .
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- HY-B0992
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-
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- HY-107030
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-
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- HY-B0318S
-
|
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Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
|
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Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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-
-
- HY-B0318A
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-
-
- HY-78644
-
|
4-nitroimidazole
|
Biochemical Assay Reagents
|
Others
|
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4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
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- HY-B1244S
-
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1,2-Dimethyl-5-nitroimidazole-d3
|
Isotope-Labeled Compounds
Antibiotic
Parasite
Bacterial
|
Infection
|
|
Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections .
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- HY-116972
-
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SR 2508
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Biochemical Assay Reagents
|
Cancer
|
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Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research .
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- HY-P4545
-
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Angiotensin Receptor
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Others
|
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Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
|
-
-
- HY-W008216S
-
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Hydroxy Dimetridazole-d3
|
Drug Metabolite
Isotope-Labeled Compounds
Parasite
|
Infection
|
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HMMNI-d3 (Hydroxy Dimetridazole-d3) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections .
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- HY-P4561
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Cathepsin
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Others
|
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-P4725
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Fluorescent Dye
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Others
|
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
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-
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- HY-D1450
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S01448
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Fluorescent Dye
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Cancer
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IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
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- HY-170779
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FAP
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Cancer
|
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DOTA-NI-FAPI-04 is a FAP inhibitor (IC50 = 7.44 nM). By integrating FAP targeting with hypoxia-sensitive groups (nitroimidazole), DOTA-NI-FAPI-04 significantly enhances tumor uptake and retention capabilities. DOTA-NI-FAPI-04 chelates metallic isotopes (such as 68Ga and 177Lu) through DOTA to produce radioactive probes ([68Ga]Ga/DOTA-NI-FAPI-04 and [177Lu]Lu/DOTA-NI-FAPI-04), which can be used for research in tumor diagnostics and therapeutic agents. DOTA-NI-FAPI-04 holds dual targeting potential in the fields of cancer imaging, tumor microenvironment analysis, and radionuclide therapy, particularly suitable for scenarios where the tumor stroma and hypoxic regions synergistically interact .
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- HY-W010433R
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2-Methyl-5-nitro-1H-imidazole (Standard)
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Reference Standards
|
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2-Methyl-5-nitroimidazole (Standard) is the analytical standard of 2-Methyl-5-nitroimidazole. This product is intended for research and analytical applications.
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- HY-119900
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Parasite
Antibiotic
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Infection
|
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Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
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- HY-136440
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Metronidazole-OH
|
Bacterial
Parasite
|
Infection
|
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Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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-
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- HY-136440R
-
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Metronidazole-OH (Standard)
|
Reference Standards
Bacterial
Parasite
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Infection
|
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Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-B0318S1
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- HY-135212S
-
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
|
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Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-136436A
-
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Drug Metabolite
Parasite
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Infection
Inflammation/Immunology
|
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Ternidazole is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole effectively alleviates chronic alcoholism. Ternidazole can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .
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- HY-W094047
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Biochemical Assay Reagents
|
Others
|
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5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-U00118R
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-
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- HY-B0177S
-
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Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa .
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- HY-121657
-
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Ro 11-2616
|
Parasite
Bacterial
|
Others
|
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Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
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- HY-15781A
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|
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Bacterial
|
Infection
|
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(R)-Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. (R)-Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
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- HY-105211
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Biochemical Assay Reagents
|
Cancer
|
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KU-2285 is an orally active fluorinated 2-nitroimidazole hypoxic cell radiosensitizer. KU-2285 has higher lipophilicity, superior sensitizing activity to Etanidazole (HY-116972), and lower neurotoxicity. KU-2285 can be used in research related to tumor diagnosis .
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- HY-135212
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|
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Endogenous Metabolite
|
Metabolic Disease
|
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Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-138094
-
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Drug Metabolite
|
Infection
|
|
N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
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-
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- HY-P11261
-
|
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PSMA
|
Cancer
|
AAZTA-NI-PSMA-093 is a bispecific agent targeting prostate-specific membrane antigen (PSMA) with an IC50 value for PSMA of 87.48 nM. AAZTA-NI-PSMA-093 has a PSMA targeting module and an oxygen-sensitivity module (hypoxia-sensitive NI-moiety). AAZTA-NI-PSMA-093 can utilize the PSMA targeting property as a "navigation system" to efficiently concentrate the entire molecule within prostate cancer cells, and once the cells are in an oxygen-deficient state, the molecule will irreversibly capture and remain in the oxygen-deficient cells, achieving "secondary enrichment". AAZTA-NI-PSMA-093 can be labeled with ⁶⁸Ga and ¹⁷⁷Lu, and has high accumulation and rapid clearance characteristics in mouse models. AAZTA-NI-PSMA-093 can be used for the study of prostate cancer .
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-
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- HY-B0508S1
-
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Ro 7-0207-13C2,15N2
|
Isotope-Labeled Compounds
Bacterial
Parasite
Antibiotic
Hedgehog
|
Infection
|
|
Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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-
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- HY-119480
-
|
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Bacterial
|
Infection
|
|
Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
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-
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- HY-N0195R
-
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2-nitroimidazole (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Azomycin (Standard) is the analytical standard of Azomycin. This product is intended for research and analytical applications. Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
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-
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- HY-119900R
-
|
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Reference Standards
Parasite
Antibiotic
|
Infection
|
|
Carnidazole (Standard) is the analytical standard of Carnidazole. This product is intended for research and analytical applications. Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
|
-
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- HY-B1244R
-
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1,2-Dimethyl-5-nitroimidazole (Standard)
|
Reference Standards
Parasite
Antibiotic
Bacterial
|
Infection
|
|
Dimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections .
|
-
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- HY-136440S1
-
|
Metronidazole-OH-d2
|
Isotope-Labeled Compounds
|
Infection
|
|
Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
|
-
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- HY-W008216R
-
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Hydroxy Dimetridazole (Standard)
|
Reference Standards
Drug Metabolite
Parasite
|
Infection
|
|
HMMNI (Standard) (Hydroxy Dimetridazole (Standard)) is the analytical standard of HMMNI (HY-W008216). This product is intended for research and analytical applications. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
|
-
-
- HY-136436R
-
|
|
Reference Standards
Endogenous Metabolite
|
Infection
Inflammation/Immunology
|
|
Ternidazole hydrochloride (Standard) is the analytical standard of Ternidazole hydrochloride (HY-136436). This product is intended for research and analytical applications. Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .
|
-
-
- HY-13801R
-
|
HOE 239 (Standard)
|
Reference Standards
Parasite
|
Infection
|
|
Fexinidazole (Standard) is the analytical standard of Fexinidazole. This product is intended for research and analytical applications. Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei .
|
-
- HY-123019
-
-
- HY-121648
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
PK 130 is a 2-nitroimidazole derivative that has radiosensitizing effects on hypoxic cells. PK 130 increases the radiosensitivity of Chinese hamster V79 cells under hypoxic conditions .
|
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- HY-B0177R
-
|
|
Reference Standards
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
|
Tinidazole (Standard) is the analytical standard of Tinidazole. This product is intended for research and analytical applications. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa .
|
-
- HY-107030R
-
|
EMD-15700 (Standard)
|
Aldehyde Dehydrogenase (ALDH)
Reference Standards
|
Metabolic Disease
|
|
Nitrefazole (Standard) is the analytical standard of Nitrefazole. This product is intended for research and analytical applications. Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.
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-
- HY-10845
-
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Bacterial
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Others
|
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CGI-17341 is a 5-nitroimidazole antibacterial agent that has the activity of inhibiting sensitive and multidrug-resistant strains of Mycobacterium tuberculosis in vitro and prolonging the survival time of mice infected with Mycobacterium tuberculosis in vivo in a dose-dependent manner.
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-
- HY-16349R
-
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K-1900 (Standard)
|
Reference Standards
Parasite
Antibiotic
|
Infection
Cancer
|
|
Nimorazole (Standard) is the analytical standard of Nimorazole. This product is intended for research and analytical applications. Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
|
-
- HY-121657R
-
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Ro 11-2616 (Standard)
|
Parasite
Bacterial
Reference Standards
|
Others
|
|
Ornidazole diol (Standard) is an analytical standard for Ornidazole diol. This product is used for research and analytical applications. Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
|
-
- HY-15781R
-
|
|
Bacterial
Reference Standards
|
Infection
|
|
Morinidazole (Standard) is the analytical standard of Morinidazole. This product is intended for research and analytical applications. Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-P4556
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-163545
-
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|
Drug Derivative
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Cancer
|
|
Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues .
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- HY-122288
-
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Bacterial
|
Infection
|
|
SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms .
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- HY-78644R
-
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5-nitroimidazole (Standard)
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Biochemical Assay Reagents
Reference Standards
|
Others
|
|
4-Nitroimidazole (Standard) is the analytical standard of 4-Nitroimidazole. This product is intended for research and analytical applications. 4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-136440S
-
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Metronidazole-OH-d4
|
Isotope-Labeled Compounds
Bacterial
Parasite
|
Infection
|
|
Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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-
- HY-135212R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-131257R
-
|
|
Drug Metabolite
Reference Standards
|
Others
Cancer
|
|
Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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-
- HY-115249R
-
|
|
Parasite
Antibiotic
Bacterial
Reference Standards
|
Infection
|
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-B0508S
-
|
Ro 7-0207-d5
|
Isotope-Labeled Compounds
Bacterial
Parasite
Antibiotic
Hedgehog
|
Infection
Cancer
|
|
Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
|
-
- HY-B0508R
-
|
Ro 7-0207 (Standard)
|
Reference Standards
Bacterial
Parasite
Antibiotic
Hedgehog
|
Infection
Cancer
|
|
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
|
-
- HY-136436S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Infection
Inflammation/Immunology
|
|
Ternidazole-d6 hydrochloride is the deuterium labeled Ternidazole hydrochloride (HY-136436). Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .
|
-
- HY-W018143
-
|
|
Bacterial
Fungal
|
Infection
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1-Methyl-4-nitroimidazole is an antibacterial agent. 1-Methyl-4-nitroimidazole is reduced by bacterial nitroreductases to form toxic derivatives, which cause DNA damage, inhibit bacterial nucleic acid synthesis, generate toxic superoxides through futile cycling of reduced radical anions, and induce bacterial cell death. 1-Methyl-4-nitroimidazole exhibits moderate in vitro activity against bacteria and fungal. 1-Methyl-4-nitroimidazole can be used in the research of skin infections, purulent infections and urinary tract infections .
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- HY-119480R
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Bacterial
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Infection
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Megazol (Standard) is the analytical standard of Megazol. This product is intended for research and analytical applications. Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
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- HY-W094047R
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Biochemical Assay Reagents
Reference Standards
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Others
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5-Chloro-1-methyl-4-nitroimidazole (Standard) is the analytical standard of 5-Chloro-1-methyl-4-nitroimidazole. This product is intended for research and analytical applications. 5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-180543
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HIV
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Infection
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HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research .
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| Cat. No. |
Product Name |
Type |
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- HY-78644
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4-nitroimidazole
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Biochemical Assay Reagents
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4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W094047
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Biochemical Assay Reagents
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5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-78644R
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5-nitroimidazole (Standard)
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Biochemical Assay Reagents
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4-Nitroimidazole (Standard) is the analytical standard of 4-Nitroimidazole. This product is intended for research and analytical applications. 4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W094047R
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Biochemical Assay Reagents
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5-Chloro-1-methyl-4-nitroimidazole (Standard) is the analytical standard of 5-Chloro-1-methyl-4-nitroimidazole. This product is intended for research and analytical applications. 5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4545
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Angiotensin Receptor
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Others
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Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
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- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-P4725
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Fluorescent Dye
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Others
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
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- HY-P11261
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PSMA
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Cancer
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AAZTA-NI-PSMA-093 is a bispecific agent targeting prostate-specific membrane antigen (PSMA) with an IC50 value for PSMA of 87.48 nM. AAZTA-NI-PSMA-093 has a PSMA targeting module and an oxygen-sensitivity module (hypoxia-sensitive NI-moiety). AAZTA-NI-PSMA-093 can utilize the PSMA targeting property as a "navigation system" to efficiently concentrate the entire molecule within prostate cancer cells, and once the cells are in an oxygen-deficient state, the molecule will irreversibly capture and remain in the oxygen-deficient cells, achieving "secondary enrichment". AAZTA-NI-PSMA-093 can be labeled with ⁶⁸Ga and ¹⁷⁷Lu, and has high accumulation and rapid clearance characteristics in mouse models. AAZTA-NI-PSMA-093 can be used for the study of prostate cancer .
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0318S
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1 Publications Verification
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Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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- HY-B1244S
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1 Publications Verification
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Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections .
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- HY-W008216S
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HMMNI-d3 (Hydroxy Dimetridazole-d3) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections .
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- HY-B0318S1
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Metronidazole-d4 is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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- HY-135212S
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Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-B0177S
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Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa .
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- HY-B0508S1
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Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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- HY-136440S1
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Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-136440S
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Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-B0508S
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Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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- HY-136436S
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Ternidazole-d6 hydrochloride is the deuterium labeled Ternidazole hydrochloride (HY-136436). Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .
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