59729-37-2

Fexinidazole Chemical Structure
59729-37-2

Chemical Structure

Fexinidazole

Synonym(s): HOE 239

  • CAS No.: 59729-37-2
  • Formula:C12H13N3O3S
  • Molecular Weight:279.31

IUPAC Name: 1-methyl-2-((4-(methylthio)phenoxy)methyl)-5-nitro-1H-imidazole

InChIKey: MIWWSGDADVMLTG-UHFFFAOYSA-N

SMILES: O=[N+](C1=CN=C(COC2=CC=C(SC)C=C2)N1C)[O-]

Biological Activity: Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei[1].

Cat. No. Product Name Purity Description Pricing
HY-13801
Fexinidazole 99.84% Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.
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HY-13801R
Fexinidazole (Standard) ≥98% Fexinidazole (Standard) is the analytical standard of Fexinidazole. This product is intended for research and analytical applications. Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.
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