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Results for "

optical rotation

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dyes

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0947
    Azure A chloride

    		DNA Stain Others
    Azure A chloride is a phenothiazine dye. Azure A chloride is an alternative DNA dye used for the separation of DNA and protein fragments in agarose gel electrophoresis and PAGE. Azure A chloride can be chemisorbed on the surface of mild steel according to the Langmuir adsorption isotherm to form a protective film. Azure A chloride binds to double-stranded DNA in a non-cooperative manner via weak intercalation, triggering molecular conformational disturbance, restricted rotational motion, and changes in optical activity .
    Azure A chloride
  • HY-103019B
    (-)-Enitociclib
    2 Publications Verification

    (R)-Enitociclib; (-)-BAY-1251152; (-)-VIP152

    		 Drug Isomer CDK Apoptosis DNA/RNA Synthesis Cancer
    (-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC + lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
    (-)-Enitociclib
  • HY-N18291
    12β-1-O-Tigloyl-1-O-deacetyl-nimbolinin B

    		Others Others
    12β-1-O-Tigloyl-1-O-deacetyl-nimbolinin B (Compound 1b) is a nimbolinin-type limonoid found in the fruits of Melia toosendan.12β-1-O-Tigloyl-1-O-deacetyl-nimbolinin B exists as a tautomer of 12α-1-O-tigloyl-1-O-deacetyl-nimbolinin B .
    12β-1-O-Tigloyl-1-O-deacetyl-nimbolinin B
  • HY-N17838
    16β-Hydroxycardiopetaline

    		Drug Derivative Others
    16β-Hydroxycardiopetaline (compound 1) is a norditerpene alkaloid.16β-Hydroxycardiopetaline can be found in the aerial parts of Aconitum variegatum L .
    16β-Hydroxycardiopetaline
  • HY-103019BR
    (-)-Enitociclib (Standard)

    (R)-Enitociclib (Standard); (-)-BAY-1251152 (Standard); (-)-VIP152 (Standard)

    		 Reference Standards Drug Isomer CDK Apoptosis DNA/RNA Synthesis Cancer
    (-)-Enitociclib (Standard) is the analytical standard of (-)-Enitociclib (HY-103019B). This product is intended for research and analytical applications. (-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
    (-)-Enitociclib (Standard)

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