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Art. -Nr.: HY-D0947

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Azure A chloride

Name: Azure A chloride
Brand: MedChemExpress
SKU: HY-D0947
Price: 30.00 USD
Availability: InStock
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Azure A chloride is a phenothiazine dye. Azure A chloride is an alternative DNA dye used for the separation of DNA and protein fragments in agarose gel electrophoresis and PAGE. Azure A chloride can be chemisorbed on the surface of mild steel according to the Langmuir adsorption isotherm to form a protective film. Azure A chloride binds to double-stranded DNA in a non-cooperative manner via weak intercalation, triggering molecular conformational disturbance, restricted rotational motion, and changes in optical activity.

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Reinheit: 70%
CAS. Nr.: 531-53-3
Formel: C₁₄H₁₄ClN₃S
Molecular Weight:291.81

Speicherung:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Azure A chloride Chemical Structure

CAS. Nr.: 531-53-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Azure A chloride (1-100 μM; 1-120 h, 298-328 K) acts as a stable, mixed-type corrosion inhibitor for mild steel in 1.0 M HCl, achieving a maximum inhibition efficiency of 88% at 100 μM after 1 h immersion at 298 K, and maintaining efficiencies above 86% even after 120 h of exposure at the highest concentration^[2].
Azure A chloride inhibits mild steel corrosion via electron donation from nitrogen atoms (N19, N30) and heterocyclic ring carbon atoms (C3, C8) to the metal surface, with enhanced electron-donor activity in aqueous acidic conditions, supporting a chemisorption mechanism^[2].
Azure A chloride (1-60 μM; incubated at 20 ± 0.5-1.0°C) binds to herring testes double-stranded DNA in a non-cooperative, weak intercalative manner with an intrinsic binding constant of ~0.88 × 10⁵/M, a binding stoichiometry of ~4.5 base pairs per dye molecule, and induces minor changes to DNA conformation and optical activity in the dye molecule^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 531-53-3
Appearance Solid
Molecular Weight 291.81
Formel C₁₄H₁₄ClN₃S
Color Brown to black
SMILES

CN(C1=CC2=[S+]C3=C(C=CC(N)=C3)N=C2C=C1)C.[Cl-]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit

In Vitro:

H₂O : < 0.1 mg/mL (insoluble)

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Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. M. Snehalatha, et al. Azure A chloride: computational and spectroscopic study. J. Raman Spectrosc. 2009, 40, 176-182.

[2]. Demet Özkır, et al. The inhibition effect of Azure A on mild steel in 1 M HCl. A complete study: Adsorption, temperature, duration and quantum chemical aspects. Corrosion Science 56 (2012) 143-152.

[3]. Paul P, et al. Spectroscopic studies on the binding interaction of phenothiazinium dyes toluidine blue O, azure A and azure B to DNA. Spectrochim Acta A Mol Biomol Spectrosc. 2013;107:303-310. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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