Azure A (chloride)
Based on 1 Customer Validation
Azure A chloride is a phenothiazine dye. Azure A chloride is an alternative DNA dye used for the separation of DNA and protein fragments in agarose gel electrophoresis and PAGE. Azure A chloride can be chemisorbed on the surface of mild steel according to the Langmuir adsorption isotherm to form a protective film. Azure A chloride binds to double-stranded DNA in a non-cooperative manner via weak intercalation, triggering molecular conformational disturbance, restricted rotational motion, and changes in optical activity.
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- 純度: 70%
- CAS 番号: 531-53-3
- 分子式: C14H14ClN3S
- 分子量:291.81
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Azure A chloride (1-100 μM; 1-120 h, 298-328 K) acts as a stable, mixed-type corrosion inhibitor for mild steel in 1.0 M HCl, achieving a maximum inhibition efficiency of 88% at 100 μM after 1 h immersion at 298 K, and maintaining efficiencies above 86% even after 120 h of exposure at the highest concentration[2].
Azure A chloride inhibits mild steel corrosion via electron donation from nitrogen atoms (N19, N30) and heterocyclic ring carbon atoms (C3, C8) to the metal surface, with enhanced electron-donor activity in aqueous acidic conditions, supporting a chemisorption mechanism[2].
Azure A chloride (1-60 μM; incubated at 20 ± 0.5-1.0°C) binds to herring testes double-stranded DNA in a non-cooperative, weak intercalative manner with an intrinsic binding constant of ~0.88 × 105/M, a binding stoichiometry of ~4.5 base pairs per dye molecule, and induces minor changes to DNA conformation and optical activity in the dye molecule[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 531-53-3
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性状 Solid
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分子量 291.81
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分子式 C14H14ClN3S
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Color Brown to black
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SMILES
CN(C1=CC2=[S+]C3=C(C=CC(N)=C3)N=C2C=C1)C.[Cl-]
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別名
アズールAクロリド
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
H2O : < 0.1 mg/mL (insoluble)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Azure A chloride 関連分類
HY-D0947 関連分類
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