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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
oscillation
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "oscillation" in MCE Product Catalog:
3
Category:
Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields
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Cat. No.: HY-175668
CAS No.: 2756581-81-2
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IDOR-1104-0086 is an orally active Kv7 potassium channel opener with an EC50 of 210 nM that can cross blood-brain barrier. IDOR-1104-0086 displays strong selectivity against the hERG channel with an IC20 of 25 μM. IDOR-1104-0086 exhibits efficacy in two rodent models of epilepsy and a favorable tolerability profile. IDOR-1104-0086 can used for the study of epilepsy .
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Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC50 of 0.18 μM. Nav1.2-IN-2 preferentially binds to the inactivated state of Nav1.2, reduces window current, suppresses neuronal depolarization and action potential generation. Nav1.2-IN-2 suppresses Veratridine (HY-N6691)-induced Ca 2+ influx. Nav1.2-IN-2 can be used for the research of epilepsy .
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Cat. No.: HY-I0626S2
CAS No.: 106391-24-6
Cat. No.: HY-P1427A
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Cat. No.: HY-123434
CAS No.: 181941-32-2
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PD-149164 is a potent agonist of cholecystokinin B (CCK-B) receptor, with IC50 values of 0.083 nM and 75 nM in binding assay to CCK-B and CCK-A .
Cat. No.: HY-I0626S1
CAS No.: 181517-10-2
Cat. No.: HY-I0626S
CAS No.: 285978-06-5
Cat. No.: HY-131041
CAS No.: 2250019-90-8
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Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Ned-K is effective at dampening simulated ischaemia and reperfusion (sIR)-induced Ca 2+ oscillations in cardiomyocytes .
Cat. No.: HY-161567
CAS No.: 2791360-37-5
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OX2R-IN-3 (Compound 53) is an orally active type 2 orexin receptor (OX2R) agonist (EC50<100 nM.) .
Cat. No.: HY-P2135
CAS No.: 130092-56-7
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Cat. No.: HY-105415
CAS No.: 142223-92-5
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U 92032 is a T-type Ca 2+ channel antagonist. U 92032 inhibits Na + channels. U-92032 inhibits thalamic oscillations. U 92032 can be used in the research of neurological diseases .
Cat. No.: HY-153164
CAS No.: 879054-55-4
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VU0606170 is a selective Slack channel inhibitor with low micromolar potency. VU0606170 can reduce the frequency of neuronal Calcium oscillations in a concentration dependent manner. VU0606170 can be used for research on diseases such as epilepsy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
