130092-56-7
Chemical Structure
Neuropeptide AF1
- CAS No.: 130092-56-7
- Formula:C45H69N13O10
- Molecular Weight:952.11
IUPAC Name: (6S,9S,12S,15S)-1-amino-6-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-15-((S)-4-amino-2-((S)-2,6-diaminohexanamido)-4-oxobutanamido)-12-benzyl-9-((S)-sec-butyl)-1-imino-8,11,14-trioxo-2,7,10,13-tetraazaoctadecan-18-oic acid
InChIKey: QMVYYEUDJVTXIK-XCWQRLKCSA-N
SMILES: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O
Biological Activity: Neuropeptide AF1 is a FMRFamide-like neuropeptide. Neuropeptide AF1 can be isolated from head extracts of the nematode Ascaris suum. Neuropeptide AF1 rapidly and reversibly abolishs slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduces their input resistances. Neuropeptide AF1 inhibits locomotory movements in intact Ascaris[1].
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Neuropeptide AF1 | Neuropeptide AF1 is a FMRFamide-like neuropeptide. Neuropeptide AF1 can be isolated from head extracts of the nematode Ascaris suum. Neuropeptide AF1 rapidly and reversibly abolishs slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduces their input resistances. Neuropeptide AF1 inhibits locomotory movements in intact Ascaris. | |||||||||||||||||||||
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Keywords
