2 Results for "

pFAK

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "pFAK" in MCE Product Catalog:

Art. -Nr.: HY-117836
CAS. Nr.: 1257994-15-2
Target:  

FAK

Forschungsgebiete:  

Cancer

FAK-IN-16 (compound OXA-11) is an orally active, selective focal adhesion kinase (FAK) inhibitor with an IC50 of 1.2 pM. FAK-IN-16 inhibits FAK phosphorylation at pFAK[Y397] and pFAK[Y861]. FAK-IN-16 slows tumor growth and reduces tumor vascularity, invasion. FAK-IN-16 potentiates effects of Cisplatin (HY-17394) on tumor cell proliferation and apoptosis in vitro and anti-tumor actions in mice .
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Art. -Nr.: HY-136699
CAS. Nr.: 78536-37-5
Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer .
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