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Results for "

polyacetylene

" in MedChemExpress (MCE) Product Catalog:

By Targets:	17β-HSD (1) Antibiotic (1) Bacterial (1) Drug Derivative (3) Fungal (1) GnRH Receptor (1) Kisspeptin Receptor (3) Lipase (2) NOD-like Receptor (NLR) (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (1) Metabolic Disease (4) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2161B

TAK-683 acetate 4 Publications Verification	Kisspeptin Receptor	Cancer
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-N1976

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol		Infection Cancer
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .

HY-P5544

M-TriDAP N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .

HY-124031

Lobetyolinin	Drug Derivative	Cardiovascular Disease Cancer
Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-N12486A

(3S,8R,9R)-Isofalcarintriol	Others	Neurological Disease Metabolic Disease Cancer
(3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .

HY-P2115

Ramorelix	GnRH Receptor	Cancer
Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .

HY-N12733

Chrysindin A	Others	Others
Chrysindin A is a polyacetylene from the flowers of Chrysanthemum indicum .

HY-N12043

Bidenoside C	Others	Others
Bidenoside C (compound 10) is a polyacetylene glycoside (Polyacetylene Glycoside), which can be isolated from the flowers of Coreopsis lanceolata (Asteraceae) .

HY-N16654

Panaxjapyne B	Others	Others
Panaxjapyne B is a polyacetylene compound. Panaxjapyne B can be isolated from roots of P. japonicus var. major .

HY-N3113

Panaxyne	Others	Cancer
Panaxyne is a polyacetylene, that can be isolated from the roots of cultivated-wild ginseng. Panaxyne shows significant and selective cytotoxicity against SK-OV-3, with an ED₅₀ of 1.40 µM .

HY-N15063

10-Hydroxyundeca-2,4,6,8-tetraynamide	Antibiotic Bacterial Fungal	Infection
10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic. 10-Hydroxyundeca-2,4,6,8-tetraynamide has anti-Gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity .

HY-P5544A

M-TriDAP TFA N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-N3064

Pilosol A	Others	Others
Pilosol A is a polyacetylene alcohol that can be isolated from Bidens pilosa L. var. minor (Blume) Sherff .

HY-N18143

12,14-Diacetate-2E,8E,10E-triene-4,6-diyn-1-ol	Others	Others
12,14-Diacetate-2E,8E,10E-triene-4,6-diyn-1-ol (Compound 26) is a polyacetylene compound that can be isolated from the rhizomes of Atractylodes lancea .

HY-N16950

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol diacetate	Drug Derivative	Others
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol diacetate is a polyacetylene that can be found in the rhizomes of Atractylodes chinensis, Atractylodes koreana, and Atractylodes japonica .

HY-N17948

Isolobetyol	Others	Cancer
Isolobetyol is a polyacetylene found in whole plants of Lobelia chinensis. Isolobetyol shows cytotoxic effects against cancer cells. Isolobetyol can be used for the research of cancer, such as human lung cancer and biphasic mesothelioma .

HY-N9181

4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol	Others	Others
4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol is a phytotoxic polyacetylene compound. 4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol can be isolated from the roots and root exudates of Acroptilon repens. It exhibits phytotoxicity and reduces the root length of lettuce .

HY-N12952

Falcarinolone	Others	Others
Falcarinolone is a polyacetylene, which is initially isolated from Aegopodium podagraria L .

HY-180915

Dehydrofalcarinol	17β-HSD	Cancer
Dehydrofalcarinol is a polyacetylene compound found in Desmanthodium guatemalense with anticancer activity. Dehydrofalcarinol shows anticancer activity depending on 17β-hydroxysteroid dehydrogenase (17β-HSD) type 11. Dehydrofalcarinol can be used for the research of triple-negative breast cancer .

HY-N7988A

(E)-4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate	Drug Derivative	Inflammation/Immunology
(E)-4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene found in the rhizomes of Atractylodes lancea. (E)-4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate shows no inhibitory activity against 5-lipoxygenase and COX-1 in in vitro assays at tested concentrations .

HY-N18257

(4E,6E,12E)-4,6,12-Tetradecatriene-8,10-diyn-1-ol	Others	Others
(4E,6E,12E)-4,6,12-Tetradecatriene-8,10-diyn-1-ol (Compound 4a) is a natural product that can be isolated from the rhizomes of Atractylis koreana .

HY-N7988

4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate	Lipase	Metabolic Disease
4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene compound found in the rhizomes of Atractylodes lancea. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate inhibits human pancreatic lipase, with an IC₅₀ of 55.67 μM and 16.7 μg/mL. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can block the digestion of triglycerides by inhibiting the activity of human pancreatic lipase. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can be used in research on obesity .

HY-N18267

(3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate	Lipase	Metabolic Disease
(3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate is a polyacetylene found in Atractylodes lancea rhizome. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate inhibits human pancreatic lipase inhibitor with an IC₅₀ of 39.91 μM. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate can be used for the research of obesity .

HY-N18265

(4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate	Others	Metabolic Disease
(4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate is a polyacetylene found in rhizomes of Atractylodes chinensis. (4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate inhibits RANKL-induced osteoclast differentiation. (4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate can be used for the research of osteoporosis .

Cat. No.	Product Name	Target	Research Area

HY-P2161B

TAK-683 acetate 4 Publications Verification	Kisspeptin Receptor	Cancer
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P5544

M-TriDAP N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P2115

Ramorelix	GnRH Receptor	Cancer
Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .

HY-P5544A

M-TriDAP TFA N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol	Infection Structural Classification Natural Products Classification of Application Fields Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Umbelliferae Plants Inflammation/Immunology Disease Research Fields Source Classification
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .

Lobetyolinin	Cardiovascular Disease Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification	Drug Derivative
Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research .

(3S,8R,9R)-Isofalcarintriol	Natural Products Artemisia granatensis boiss Umbelliferae Plants Source Classification	Others
(3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .

Chrysindin A	Natural Products Erythrina abyssinica Lam. Plants Compositae Source Classification	Others
Chrysindin A is a polyacetylene from the flowers of Chrysanthemum indicum .

Bidenoside C	Coreopsis lanceolata L. Plants Compositae Saccharides Monosaccharides Source Classification	Others
Bidenoside C (compound 10) is a polyacetylene glycoside (Polyacetylene Glycoside), which can be isolated from the flowers of Coreopsis lanceolata (Asteraceae) .

Panaxjapyne B	Structural Classification Natural Products Panax japonicas C. A. Mey. Plants Araliaceae Source Classification	Others
Panaxjapyne B is a polyacetylene compound. Panaxjapyne B can be isolated from roots of P. japonicus var. major .

Panaxyne	Panax ginseng C. A. Meyer Natural Products Plants Araliaceae Source Classification	Others
Panaxyne is a polyacetylene, that can be isolated from the roots of cultivated-wild ginseng. Panaxyne shows significant and selective cytotoxicity against SK-OV-3, with an ED₅₀ of 1.40 µM .

10-Hydroxyundeca-2,4,6,8-tetraynamide	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Fungal
10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic. 10-Hydroxyundeca-2,4,6,8-tetraynamide has anti-Gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity .

Pilosol A	Structural Classification Other Phenylpropanoids Amburana cearensis (Allemão) A.C.Sm. Phenylpropanoids Plants Compositae Source Classification	Others
Pilosol A is a polyacetylene alcohol that can be isolated from Bidens pilosa L. var. minor (Blume) Sherff .

12,14-Diacetate-2E,8E,10E-triene-4,6-diyn-1-ol	Structural Classification Natural Products Plants Compositae Source Classification Erythrina sigmoidea Hua	Others
12,14-Diacetate-2E,8E,10E-triene-4,6-diyn-1-ol (Compound 26) is a polyacetylene compound that can be isolated from the rhizomes of Atractylodes lancea .

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol diacetate	Structural Classification Terpenoids Diterpenoids Plants Compositae Source Classification Erythrina sigmoidea Hua	Drug Derivative
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol diacetate is a polyacetylene that can be found in the rhizomes of Atractylodes chinensis, Atractylodes koreana, and Atractylodes japonica .

Isolobetyol	Structural Classification Natural Products Campanulaceae Plants Lobelia chinensis Lour. Source Classification	Others
Isolobetyol is a polyacetylene found in whole plants of Lobelia chinensis. Isolobetyol shows cytotoxic effects against cancer cells. Isolobetyol can be used for the research of cancer, such as human lung cancer and biphasic mesothelioma .

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polyacetylene

Inhibitors & Agonists

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